Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28265423 | 0.98 | ALDH1A1 (0.57) | ALDH1A1NPSR1TSHRL3MBTL1KDM4E | |
| SCHEMBL30773006 | 0.98 | ALDH1A1 (0.57) | ALDH1A1NPSR1TSHRL3MBTL1KDM4E | |
| SCHEMBL3385655 | 0.92 | L3MBTL1 (0.51) | ALDH1A1NPSR1TSHRL3MBTL1KDM4E | |
| SCHEMBL334541 | 0.90 | ALDH1A1 (0.59) | ALDH1A1NPSR1TSHRL3MBTL1KDM4E | |
| SCHEMBL1433202 | 0.88 | ALDH1A1 (0.62) | ALDH1A1NPSR1TSHRL3MBTL1KDM4E | |
| SCHEMBL17793351 | 0.88 | ALDH1A1 (0.62) | ALDH1A1NPSR1TSHRL3MBTL1KDM4E | |
| SCHEMBL31409193 | 0.88 | ALDH1A1 (0.62) | ALDH1A1NPSR1TSHRL3MBTL1KDM4E | |
| SCHEMBL18022794 | 0.88 | ALDH1A1 (0.62) | ALDH1A1NPSR1TSHRL3MBTL1KDM4E | |
| SCHEMBL9451713 | 0.86 | L3MBTL1 (0.58) | ALDH1A1NPSR1TSHRL3MBTL1KDM4E | |
| SCHEMBL3096958 | 0.85 | TSHR (0.56) | ALDH1A1NPSR1TSHRL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE44186-E1 | Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-04-30 | — | — | US | disclosed |
| EP-1730204-B1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE SRL (IT) | 2011-08-10 | — | — | EP | disclosed |
| US-7550471-B2 | 5-alkyl-7-aminotriazolopyrimidines, methods and intermediary product necessary for the production thereof, agents containing said compounds and the use thereof for fighting against harmful mushrooms | BASF AKTIENGESELLSCHAFT (DE) | 2009-06-23 | — | — | US | disclosed |
| US-7544748-B2 | Components and catalysis for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2009-06-09 | — | — | US | disclosed |
| US-20090137557-A1 | Calcilytic Compounds | SMITHKLINE BEECHAM CORPORATION | 2009-05-28 | — | — | US | disclosed |
| CN-101360498-A | Calcilytic compounds | SMITHKLINE BEECHAM CORP (US) | 2009-02-04 | — | — | CN | disclosed |
| EP-1951244-A2 | CALCILYTIC COMPOUNDS | SmithKline Beecham Corporation (US) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007113136-A1 | USE OF SUBSTITUTED TRIAZOLOPYRIMIDINES FOR CONTROLLING PHYTOPATHOGENIC HARMFUL FUNGI | BASF AKTIENGESELLSCHAFT (DE) | 2007-10-11 | — | — | WO | disclosed |
| US-20070208150-A1 | Components and Catalysis for the Polymerization of Olefins | BASELL POLIOLEFINE ITALIA S.R.L (IT) | 2007-09-06 | — | — | US | disclosed |
| WO-2007062370-A2 | CALCILYTIC COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-05-31 | — | — | WO | disclosed |
| EP-1730204-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2006-12-13 | — | — | EP | disclosed |
| EP-1585747-B1 | 5-ALKYL-7-AMINOTRIAZOLOPYRIMIDINES, METHODS AND INTERMEDIATES SUITABLE FOR THEIR PRODUCTION, AGENTS CONTAINING THEM AND THEIR USE FOR CONTROLLING HARMFUL FUNGI | BASF AG (DE) | 2006-09-13 | — | — | EP | disclosed |
| US-20050272749-A1 | 5-Alkyl-7-aminotriazolopyrimidines, methods and intermediary product necessary for the production thereof, agents containing said compounds and the use thereof for fighting against harmful mushrooms | BASF AKTIENGESELLSCHAFT (DE) | 2005-12-08 | — | — | US | disclosed |
| WO-2005097841-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2005-10-20 | — | — | WO | disclosed |
| EP-1585747-A1 | 5-ALKYL-7-AMINOTRIAZOLOPYRIMIDINES, METHODS AND INTERMEDIARY PRODUCTS NECESSARY FOR THE PRODUCTION THEREOF, AGENTS CONTAINING SAID COMPOUNDS AND THE USE THEREOF FOR FIGHTING AGAINST HARMFUL MUSHROOMS | BASF Aktiengesellschaft (DE) | 2005-10-19 | — | — | EP | disclosed |
| WO-2004041825-A1 | 5-ALKYL-7-AMINOTRIAZOLOPYRIMIDINES, METHODS AND INTERMEDIARY PRODUCTS NECESSARY FOR THE PRODUCTION THEREOF, AGENTS CONTAINING SAID COMPOUNDS AND THE USE THEREOF FOR FIGHTING AGAINST HARMFUL MUSHROOMS | BASF AKTIENGESELLSCHAFT (DE) | 2004-05-21 | — | — | WO | disclosed |
| US-6265421-B1 | DILATATION OF ARTERIES | ORION CORPORATION (FI) | 2001-07-24 | — | — | US | disclosed |
| US-5968959-A | ADMINISTERING PHOSPHOLAMBAN INHIBITOR | ORION CORPORATION (FI) | 1999-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050272749-A1 | 5-Alkyl-7-aminotriazolopyrimidines, methods and intermediary product necessary for the production thereof, agents containing said compounds and the use thereof for fighting against harmful mushrooms | ERG28, CBR3, CBR1 | ALDH1A1 850/4885NPSR1 3243/4885TSHR 3723/4885 |
| US-20090137557-A1 | Calcilytic Compounds | CALCR, SOST, CALCB | ALDH1A1 4674/4885NPSR1 920/4885TSHR 3409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.