Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23176772 | 0.91 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2ALMNAFFAR1 | |
| SCHEMBL23177029 | 0.89 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL23177031 | 0.88 | LMNA (0.51) | ALDH1A1LMNAFFAR1SMN1; SMN2NPC1 | |
| SCHEMBL23169316 | 0.85 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2ALMNAFFAR1 | |
| SCHEMBL14568385 | 0.81 | MEN1 (0.41) | ALDH1A1MEN1KMT2ALMNAHTT | |
| SCHEMBL24835469 | 0.79 | SMN1; SMN2 (0.41) | ALDH1A1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL25986454 | 0.75 | ALDH1A1 (0.43) | ALDH1A1LMNASMN1; SMN2RAB9AHTT | |
| SCHEMBL13172453 | 0.71 | ALDH1A1 (0.42) | ALDH1A1LMNAFFAR1SMN1; SMN2NPC1 | |
| SCHEMBL15294398 | 0.71 | TRPA1 (0.46) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL3268541 | 0.70 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021057061-A1 | SENOLYTIC AND ANTIINFLAMMATORY PRODRUGS AND METHODS OF USE THEREOF | PEKING UNIVERSITY (CN) | 2021-04-01 | — | — | WO | disclosed |
| WO-2021056996-A1 | SENOLYTIC AND ANTIINFLAMMATORY PRODRUGS AND METHODS OF USE THEREOF | PEKING UNIVERSITY (CN) | 2021-04-01 | — | — | WO | disclosed |