Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25986454 | 0.84 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1LMNAHTTGAA | |
| SCHEMBL23169316 | 0.81 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1LMNAHTTGAA | |
| SCHEMBL23176772 | 0.79 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1LMNAHTTGAA | |
| SCHEMBL23169233 | 0.79 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1LMNAHTTGAA | |
| SCHEMBL7823977 | 0.76 | KMT2A (0.53) | SMN1; SMN2ALDH1A1LMNAHTTPKM | |
| SCHEMBL15858815 | 0.76 | TSHR (0.56) | SMN1; SMN2ALDH1A1LMNAGAAS1PR4 | |
| SCHEMBL9944267 | 0.76 | IDO1 (0.59) | ALDH1A1LMNAMAPTRAB9ANPC1 | |
| SCHEMBL1135919 | 0.75 | HSPB1 (0.50) | ALDH1A1S1PR4RAB9A | |
| SCHEMBL14453659 | 0.73 | MASP2 (0.54) | SMN1; SMN2ALDH1A1LMNAGAAMAPT | |
| SCHEMBL27578149 | 0.72 | TTR (0.53) | SMN1; SMN2ALDH1A1LMNAHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230001024-A1 | CROSS-LINKING COMPOUNDS AND METHODS OF USE THEREOF | NORTH CAROLINA STATE UNIVERSITY | 2023-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230001024-A1 | CROSS-LINKING COMPOUNDS AND METHODS OF USE THEREOF | AOX1, MTCL3, COL1A1 | SMN1; SMN2 2650/4885ALDH1A1 74/4885LMNA 922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.