Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 3/20 | 0.36 |
| ▸ | USP10 | Q14694 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.36 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2987873 | 0.88 | GPR35 (0.44) | GPR35SNCAHTTMAPTLMNA | |
| SCHEMBL23177029 | 0.82 | ALDH1A1 (0.53) | MEN1KMT2AHTTLMNAALDH1A1 | |
| SCHEMBL15294398 | 0.82 | TRPA1 (0.46) | MEN1KMT2AMAPTLMNACYP1A2 | |
| SCHEMBL23169233 | 0.81 | ALDH1A1 (0.41) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL23177031 | 0.81 | LMNA (0.51) | HTTMAPTLMNAALDH1A1GAA | |
| SCHEMBL2346437 | 0.76 | GPR35 (0.51) | GPR35SNCATHRBMAPTLMNA | |
| SCHEMBL2742136 | 0.76 | MEN1 (0.50) | MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL358269 | 0.75 | TSHR (0.52) | LMNACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL14905850 | 0.74 | CYP2C9 (0.42) | MEN1KMT2ACYP2C9 | |
| SCHEMBL21677249 | 0.74 | MAPT (0.50) | MEN1KMT2AHTTMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007030366-A1 | REGIOSELECTIVE PROCESS FOR PREPARING BENZIMIDAZOLE THIOPHENES | SMITHKLINE BEECHAM CORPORATION (US) | 2007-03-15 | — | — | WO | disclosed |