Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 18/20 | 0.55 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29563539 | 0.81 | PSIP1 (0.50) | — | |
| SCHEMBL23174400 | 0.79 | PTGS2 (0.50) | PTGS2 | |
| SCHEMBL28022299 | 0.78 | PTGS2 (0.73) | PTGS2HSD11B1 | |
| SCHEMBL3243293 | 0.76 | PTGS2 (0.68) | PTGS2 | |
| SCHEMBL10300269 | 0.75 | PTGS2 (0.62) | PTGS2 | |
| SCHEMBL7677302 | 0.75 | PTGS2 (0.62) | PTGS2 | |
| SCHEMBL23174407 | 0.74 | HTR2A (0.40) | — | |
| SCHEMBL5052857 | 0.74 | PTGS2 (0.74) | PTGS2 | |
| SCHEMBL9420134 | 0.73 | PTGS2 (0.49) | PTGS2 | |
| SCHEMBL3576210 | 0.73 | NR1H2 (0.50) | PTGS2HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220402867-A1 | SULFO-SUBSTITUTED BIARYL COMPOUND OR SALT THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF | SHANGHAI LITEDD CO., LTD. (CN) | 2022-12-22 | — | — | US | disclosed |
| EP-4039674-A1 | SULFO-SUBSTITUTED BIARYL COMPOUND OR SALT THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF | Shanghai Litedd Co., Ltd. (CN) | 2022-08-10 | — | — | EP | disclosed |
| CN-112851557-B | Sulfo-substituted biaryl compound or salt thereof, and preparation method and application thereof | 上海辉启生物医药科技有限公司 | 2022-06-10 | — | — | CN | disclosed |
| CN-114502532-A | Sulfo-substituted biaryl compound or salt thereof, and preparation method and application thereof | 上海辉启生物医药科技有限公司 | 2022-05-13 | — | — | CN | disclosed |
| WO-2021063362-A1 | SULFO-SUBSTITUTED BIARYL COMPOUND OR SALT THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海辉启生物医药科技有限公司 | 2021-04-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220402867-A1 | SULFO-SUBSTITUTED BIARYL COMPOUND OR SALT THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF | RORB, RORA, RORC | PTGS2 4301/4885HSD11B1 15/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.