Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LTC4S | Q16873 | 7/20 | 0.40 |
| ▸ | RHOA | P61586 | 2/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | PTGIR | P43119 | 1/20 | 0.36 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL231747 | 0.90 | LTC4S (0.44) | LMNAL3MBTL1LTC4SRHOACXCR3 | |
| SCHEMBL232232 | 0.85 | LMNA (0.50) | LMNAL3MBTL1LTC4SMEN1KMT2A | |
| SCHEMBL230183 | 0.82 | LTC4S (0.38) | LMNAL3MBTL1LTC4S | |
| SCHEMBL232400 | 0.80 | HPGD (0.46) | LMNAL3MBTL1LTC4SMEN1KMT2A | |
| SCHEMBL231253 | 0.77 | LMNA (0.46) | LMNAL3MBTL1LTC4SMEN1KMT2A | |
| SCHEMBL232108 | 0.77 | MAPT (0.44) | LMNAL3MBTL1LTC4SMEN1KMT2A | |
| SCHEMBL231986 | 0.76 | RAB9A (0.47) | LMNAL3MBTL1MEN1KMT2AHSD17B10 | |
| SCHEMBL230032 | 0.75 | MAPT (0.44) | LMNAL3MBTL1LTC4SMEN1KMT2A | |
| SCHEMBL229900 | 0.75 | TUBB4A (0.45) | LMNAL3MBTL1LTC4SMEN1KMT2A | |
| SCHEMBL2743206 | 0.74 | LTC4S (0.49) | LMNAL3MBTL1LTC4SPTGIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120004228-A1 | Bis Aromatic Compounds for Use as LTC4 Synthase Inhibitors | BIOLIPOX AB (SW) | 2012-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004228-A1 | Bis Aromatic Compounds for Use as LTC4 Synthase Inhibitors | LTC4S, LTB4R2, LTB4R | LMNA 1141/4885L3MBTL1 324/4885LTC4S 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.