Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPG | P10696 | 12/20 | 0.58 |
| ▸ | ALPL | P05186 | 11/20 | 0.58 |
| ▸ | GCGR | P47871 | 2/20 | 0.58 |
| ▸ | TOP1 | P11387 | 2/20 | 0.52 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | APEX1 | P27695 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PLAA | Q9Y263 | 3/20 | 0.42 |
| ▸ | ALPP | P05187 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26320537 | 0.90 | ALPL (0.47) | ALPGALPLGCGRTOP1HSD17B1 | |
| SCHEMBL11429532 | 0.78 | SMN1; SMN2 (0.48) | MAPTPOLBGAARECQLHPGD | |
| SCHEMBL23196654 | 0.77 | SMN1; SMN2 (0.44) | ALPGALPLGCGRKDM4EMAPT | |
| SCHEMBL25759375 | 0.77 | MAPT (0.50) | KDM4EMAPTPOLBGAARECQL | |
| SCHEMBL3466913 | 0.73 | ALPG (1.00) | ALPGALPLGCGRTOP1KDM4E | |
| SCHEMBL11499868 | 0.72 | SMN1; SMN2 (0.39) | MAPTPOLBRECQLHPGDSMN1; SMN2 | |
| SCHEMBL23196653 | 0.72 | ALPL (0.59) | ALPGALPLGCGRTOP1HSD17B1 | |
| SCHEMBL20875226 | 0.71 | PAX8 (0.44) | KDM4EMAPTPOLBGAAHPGD | |
| SCHEMBL19403461 | 0.71 | PAX8 (0.44) | KDM4EMAPTPOLBGAAHPGD | |
| SCHEMBL26320872 | 0.70 | CA12 (0.47) | ALPGALPLTOP1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230293499-A1 | COMPOSITIONS AND METHODS FOR INHIBITING CARP-1 BINDING TO NEMO | US GOV VETERANS AFFAIRS (US) | 2023-09-21 | — | — | US | disclosed |
| US-20210106567-A1 | COMPOSITIONS AND METHODS FOR INHIBITING CARP-1 BINDING TO NEMO | US GOV VETERANS AFFAIRS (US) | 2021-04-15 | — | — | US | disclosed |
| WO-2021067572-A2 | COMPOSITIONS AND METHODS FOR INHIBITING CARP-1 BINDING TO NEMO | UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (US) | 2021-04-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210106567-A1 | COMPOSITIONS AND METHODS FOR INHIBITING CARP-1 BINDING TO NEMO | NFKBIA, NCBP1, NFKB1 | ALPG 4545/4885ALPL 4374/4885GCGR 4625/4885 |
| US-20230293499-A1 | COMPOSITIONS AND METHODS FOR INHIBITING CARP-1 BINDING TO NEMO | NFKBIA, NCBP1, NFKB1 | ALPG 4545/4885ALPL 4374/4885GCGR 4625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.