Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 9/20 | 0.59 |
| ▸ | ALPG | P10696 | 9/20 | 0.59 |
| ▸ | GCGR | P47871 | 2/20 | 0.59 |
| ▸ | TOP1 | P11387 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.47 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26320536 | 0.90 | ALPL (0.47) | ALPLALPGGCGRTOP1MAPT | |
| SCHEMBL16625012 | 0.77 | ALDH1A1 (0.60) | MAPTALDH1A1LMNAHTTKMT2A | |
| SCHEMBL23196652 | 0.76 | MAPT (0.45) | ALPLALPGGCGRMAPTALDH1A1 | |
| SCHEMBL3466913 | 0.74 | ALPG (1.00) | ALPLALPGGCGRTOP1MAPT | |
| SCHEMBL6200420 | 0.73 | HSD11B1 (0.66) | MAPTALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL7905772 | 0.72 | ALDH1A1 (0.65) | MAPTALDH1A1LMNAHTTKMT2A | |
| SCHEMBL23196655 | 0.72 | ALPG (0.58) | ALPLALPGGCGRTOP1MAPT | |
| SCHEMBL30149949 | 0.71 | ALDH1A1 (0.67) | MAPTALDH1A1LMNAHTTKMT2A | |
| SCHEMBL3595617 | 0.71 | ALDH1A1 (0.67) | MAPTALDH1A1LMNAHTTKMT2A | |
| SCHEMBL9636277 | 0.70 | ALDH1A1 (0.65) | MAPTALDH1A1LMNAHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230293499-A1 | COMPOSITIONS AND METHODS FOR INHIBITING CARP-1 BINDING TO NEMO | US GOV VETERANS AFFAIRS (US) | 2023-09-21 | — | — | US | disclosed |
| US-20210106567-A1 | COMPOSITIONS AND METHODS FOR INHIBITING CARP-1 BINDING TO NEMO | US GOV VETERANS AFFAIRS (US) | 2021-04-15 | — | — | US | disclosed |
| WO-2021067572-A2 | COMPOSITIONS AND METHODS FOR INHIBITING CARP-1 BINDING TO NEMO | UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (US) | 2021-04-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210106567-A1 | COMPOSITIONS AND METHODS FOR INHIBITING CARP-1 BINDING TO NEMO | NFKBIA, NCBP1, NFKB1 | ALPL 4374/4885ALPG 4545/4885GCGR 4625/4885 |
| US-20230293499-A1 | COMPOSITIONS AND METHODS FOR INHIBITING CARP-1 BINDING TO NEMO | NFKBIA, NCBP1, NFKB1 | ALPL 4374/4885ALPG 4545/4885GCGR 4625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.