Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 4/20 | 0.47 |
| ▸ | ALPG | P10696 | 4/20 | 0.47 |
| ▸ | GCGR | P47871 | 1/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.43 |
| ▸ | TOP1 | P11387 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 8/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23196655 | 0.90 | ALPG (0.58) | ALPLALPGGCGRHSD17B1HSD17B2 | |
| SCHEMBL26320532 | 0.78 | RAB9A (0.40) | MAPTKDM4ESMN1; SMN2RAB9ANPC1 | |
| SCHEMBL25759375 | 0.77 | MAPT (0.50) | CYP1A2CYP2C19MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL11429532 | 0.75 | SMN1; SMN2 (0.48) | CYP1A2CYP2C9CYP2C19MAPTSMN1; SMN2 | |
| SCHEMBL26320568 | 0.75 | ALPL (0.80) | ALPLALPGGCGRCYP1A2CYP3A4 | |
| SCHEMBL26320536 | 0.74 | ALPL (0.47) | ALPLALPGGCGRHSD17B1HSD17B2 | |
| SCHEMBL26320518 | 0.71 | HSD17B1 (0.38) | ALPLALPGHSD17B1HSD17B2CYP1A2 | |
| SCHEMBL20875226 | 0.71 | PAX8 (0.44) | CYP1A2CYP2C19MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL19403461 | 0.71 | PAX8 (0.44) | CYP1A2CYP2C19MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL11499868 | 0.70 | SMN1; SMN2 (0.39) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230293499-A1 | COMPOSITIONS AND METHODS FOR INHIBITING CARP-1 BINDING TO NEMO | US GOV VETERANS AFFAIRS (US) | 2023-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230293499-A1 | COMPOSITIONS AND METHODS FOR INHIBITING CARP-1 BINDING TO NEMO | NFKBIA, NCBP1, NFKB1 | ALPL 4374/4885ALPG 4545/4885GCGR 4625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.