Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.42 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.41 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.41 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL195525 | 0.87 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL10639607 | 0.83 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL10338454 | 0.82 | ALDH1A1 (0.45) | ALDH1A1MAPTHTTRAB9A | |
| SCHEMBL9020004 | 0.81 | CCR5 (0.41) | SMN1; SMN2ALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL13713047 | 0.81 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL10639422 | 0.80 | TPSAB1 (0.50) | SMN1; SMN2ALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL23557949 | 0.79 | SIGMAR1 (0.43) | SMN1; SMN2ALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL10817215 | 0.79 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL13712608 | 0.79 | SMN1; SMN2 (0.52) | SMN1; SMN2ALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL10636257 | 0.79 | TPSAB1 (0.49) | SMN1; SMN2ALDH1A1LMNAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12084445-B2 | Broad-spectrum carbapenems | VenatoRx Pharmaceuticals, Inc. (US) | 2024-09-10 | — | — | US | disclosed |
| US-20210188851-A1 | BROAD-SPECTRUM CARBAPENEMS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-06-24 | — | — | US | disclosed |
| EP-3802538-A1 | BROAD-SPECTRUM CARBAPENEMS | Venatorx Pharmaceuticals, Inc. (US) | 2021-04-14 | — | — | EP | disclosed |
| CN-112513043-A | Broad spectrum carbapenems | 维纳拓尔斯制药公司 | 2021-03-16 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210188851-A1 | BROAD-SPECTRUM CARBAPENEMS | MGAM, ALPI, SI | SMN1; SMN2 2268/4885ALDH1A1 3603/4885LMNA 1640/4885 |
| US-12084445-B2 | Broad-spectrum carbapenems | MGAM, ALPI, SI | SMN1; SMN2 2268/4885ALDH1A1 3603/4885LMNA 1640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.