Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | ERN1 | O75460 | 1/20 | 0.44 |
| ▸ | HSD17B14 | Q9BPX1 | 5/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.39 |
| ▸ | TERT | O14746 | 3/20 | 0.37 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | CTSA | P10619 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2325020 | 0.88 | HSD17B14 (0.44) | KMOHSD11B1HSD17B14HSD17B1HSD17B2 | |
| SCHEMBL5981646 | 0.86 | NPC1 (0.44) | ERN1HSD17B14HSD17B1HSD17B2TERT | |
| SCHEMBL18002037 | 0.86 | TERT (0.49) | KMOHSD17B14HSD17B1HSD17B2TERT | |
| SCHEMBL10268449 | 0.79 | CCR1 (0.52) | KMOHSD11B1HSD17B14HSD17B1HSD17B2 | |
| SCHEMBL12539129 | 0.79 | HSD17B14 (0.51) | KMOHSD17B14TERTCTSACNR2 | |
| SCHEMBL28079062 | 0.78 | TERT (0.48) | KMOTERT | |
| SCHEMBL30598255 | 0.77 | TERT (0.49) | HSD17B14TERT | |
| SCHEMBL2321964 | 0.77 | SMN1; SMN2 (0.41) | HSD11B1TERT | |
| SCHEMBL1914634 | 0.77 | TERT (0.49) | HSD17B14TERT | |
| SCHEMBL12537901 | 0.77 | KMO (0.50) | KMOTERTCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |