Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 3/20 | 0.63 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.51 |
| ▸ | CDK2AP1 | O14519 | 1/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 4/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.48 |
| ▸ | WNT1 | P04628 | 3/20 | 0.48 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | NRAS | P01111 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | CDK7 | P50613 | 1/20 | 0.43 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.43 |
| ▸ | CCNH | P51946 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31188553 | 0.79 | IRAK4 (0.53) | PIM1IRAK4CNR2DYRK1AWNT1 | |
| SCHEMBL31188580 | 0.78 | DGAT2 (0.53) | PIM1CDK2AP1CHEK1DYRK1AWNT1 | |
| SCHEMBL18918839 | 0.78 | ULK1 (0.51) | PIM1CNR2USP30PARP1 | |
| SCHEMBL4221004 | 0.78 | ALDH1A1 (0.59) | CDK2AP1CHEK1DYRK1AWNT1ALDH1A1 | |
| SCHEMBL4221000 | 0.78 | ALDH1A1 (0.59) | CDK2AP1CHEK1DYRK1AWNT1ALDH1A1 | |
| SCHEMBL16731036 | 0.78 | ALDH1A1 (0.59) | CDK2AP1CHEK1DYRK1AWNT1ALDH1A1 | |
| SCHEMBL14688609 | 0.78 | PIM1 (1.00) | PIM1DYRK1AWNT1 | |
| SCHEMBL23201601 | 0.78 | USP30 (0.57) | PIM1IRAK4CNR2DYRK1AWNT1 | |
| SCHEMBL31188609 | 0.78 | USP30 (0.57) | PIM1IRAK4CNR2DYRK1AWNT1 | |
| SCHEMBL23201605 | 0.78 | USP30 (0.57) | PIM1IRAK4CNR2DYRK1AWNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3802500-B1 | MELANOCORTIN SUBTYPE-2 RECEPTOR (MC2R) ANTAGONISTS AND USES THEREOF | CRINETICS PHARMACEUTICALS INC (US) | 2026-05-27 | — | — | EP | claimed |
| EP-3802500-A1 | MELANOCORTIN SUBTYPE-2 RECEPTOR (MC2R) ANTAGONISTS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. (US) | 2021-04-14 | — | — | EP | claimed |
| EP-3802500-A1 | MELANOCORTIN SUBTYPE-2 RECEPTOR (MC2R) ANTAGONISTS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. (US) | 2021-04-14 | — | — | EP | disclosed |