SCHEMBL23210656

SCHEMBL23210656

O=C(O)c1ccc(Oc2ccc(C3[C@H]4C[C@@H]5C[C@@H](C[C@H]3C5)C4)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 3/20 0.49
PARP15 Q460N3 2/20 0.49
SRD5A2 P31213 5/20 0.47
HSD11B1 P28845 1/20 0.44
RXRA P19793 1/20 0.42
RXRB P28702 1/20 0.42
RXRG P48443 1/20 0.42
ALDH1A1 P00352 2/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
LMNA P02545 1/20 0.41
CASP3 P42574 1/20 0.41
SENP8 Q96LD8 1/20 0.41
SENP6 Q9GZR1 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
HSD17B10 Q99714 1/20 0.39
PDE4A P27815 1/20 0.39
PDE4B Q07343 1/20 0.39
PDE4C Q08493 1/20 0.39
PDE4D Q08499 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23210653 1.00 PARP10 (0.49) PARP10PARP15SRD5A2HSD11B1RXRA
SCHEMBL21628522 0.86 PARP10 (0.58) PARP10PARP15ALDH1A1CA1CA2
SCHEMBL21628520 0.86 PARP10 (0.58) PARP10PARP15ALDH1A1CA1CA2
SCHEMBL2710730 0.85 HSD11B1 (0.41) PARP10PARP15SRD5A2HSD11B1RXRA
SCHEMBL23210684 0.84 MAPT (0.43) POLBL3MBTL1MAPT
SCHEMBL23210687 0.84 MAPT (0.43) POLBL3MBTL1MAPT
SCHEMBL21656813 0.84 CA1 (0.47) ALDH1A1CA1CA2TDP1HSD17B10
SCHEMBL23210634 0.84 CA1 (0.47) ALDH1A1CA1CA2TDP1HSD17B10
SCHEMBL21628671 0.84 HDAC6 (0.45) CA1CA2HPGD
SCHEMBL2709664 0.83 MMP13 (0.38) PARP10PARP15HSD11B1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12600696-B2 Aromatic compounds Xeniopro GmbH (DE) 2026-04-14 US disclosed
US-20230150923-A1 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2023-05-18 US disclosed
US-20210107863-A2 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2021-04-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150923-A1 NOVEL AROMATIC COMPOUNDS AHR, TYR, MUSK PARP10 1944/4885PARP15 2818/4885SRD5A2 2489/4885
US-20210107863-A2 NOVEL AROMATIC COMPOUNDS AHR, TYR, MUSK PARP10 1944/4885PARP15 2818/4885SRD5A2 2489/4885
US-12600696-B2 Aromatic compounds CCR1, CCRL2, AHR PARP10 3512/4885PARP15 4342/4885SRD5A2 1434/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.