Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.71 |
| ▸ | HTR2A | P28223 | 7/20 | 0.50 |
| ▸ | HTR2C | P28335 | 5/20 | 0.50 |
| ▸ | HTR2B | P41595 | 5/20 | 0.50 |
| ▸ | HTR1A | P08908 | 4/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.45 |
| ▸ | HTR1B | P28222 | 2/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | HTR5A | P47898 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27085094 | 0.83 | HTR6 (1.00) | HTR6HTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL30630326 | 0.83 | HTR6 (1.00) | HTR6HTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL21333087 | 0.82 | HTR2A (0.68) | HTR6HTR2AHTR2CSLC6A4MTNR1A | |
| SCHEMBL30630328 | 0.82 | HTR6 (0.68) | HTR6HTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL27084668 | 0.82 | HTR6 (0.68) | HTR6HTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL14907345 | 0.81 | HTR6 (0.75) | HTR6HTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL27085080 | 0.81 | HTR6 (0.70) | HTR6HTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL30630330 | 0.81 | HTR6 (0.70) | HTR6HTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL30630327 | 0.80 | HTR6 (0.68) | HTR6HTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL27084740 | 0.80 | HTR6 (0.68) | HTR6HTR2AHTR2CHTR2BHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210108238-A1 | PROCESSES FOR THE PRODUCTION OF TRYPTAMINES | HERCULES CAPITAL, INC. | 2021-04-15 | — | — | US | claimed |
| US-12595497-B2 | Processes for the production of tryptamines | COMPASS PATHFINDER LIMITED (GB) | 2026-04-07 | — | — | US | disclosed |
| US-20240084344-A1 | PROCESSES FOR THE PRODUCTION OF TRYPTAMINES | COMPASS PATHFINDER LIMITED (GB) | 2024-03-14 | — | — | US | disclosed |
| US-11661617-B2 | Processes for the production of tryptamines | COMPASS PATHFINDER LIMITED (GB) | 2023-05-30 | — | — | US | disclosed |
| US-11136293-B2 | Processes for the production of tryptamines | NEW ATLAS BIOTECHNOLOGIES LLC (US) | 2021-10-05 | — | — | US | disclosed |
| US-20210277433-A1 | PROCESSES FOR THE PRODUCTION OF TRYPTAMINES | HERCULES CAPITAL, INC. | 2021-09-09 | — | — | US | disclosed |
| US-20210108238-A1 | PROCESSES FOR THE PRODUCTION OF TRYPTAMINES | HERCULES CAPITAL, INC. | 2021-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12595497-B2 | Processes for the production of tryptamines | INMT, TPH1, TPH2 | HTR6 34/4885HTR2A 67/4885HTR2C 38/4885 |
| US-11661617-B2 | Processes for the production of tryptamines | TPH1, TPH2, AANAT | HTR6 22/4885HTR2A 38/4885HTR2C 153/4885 |
| US-20240084344-A1 | PROCESSES FOR THE PRODUCTION OF TRYPTAMINES | TPH1, TPH2, AANAT | HTR6 22/4885HTR2A 38/4885HTR2C 153/4885 |
| US-11136293-B2 | Processes for the production of tryptamines | TPH1, TPH2, AANAT | HTR6 22/4885HTR2A 38/4885HTR2C 153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.