Chlorpyrifos-Methyl

Chlorpyrifos-Methyl

SCHEMBL23212099

CCOP(=S)(OCC)SCCl.COP(=S)(OC)Oc1nc(Cl)c(Cl)cc1Cl

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.67
MEN1 O00255 3/20 0.67
KMT2A Q03164 3/20 0.67
CYP3A4 P08684 3/20 0.66
HSD17B10 Q99714 3/20 0.66
ALDH1A1 P00352 3/20 0.66
MAPT P10636 2/20 0.66
ALOX15 P16050 1/20 0.66
TSHR P16473 1/20 0.66
ALOX12 P18054 1/20 0.66
MAPK1 P28482 1/20 0.66
ATM Q13315 1/20 0.66
L3MBTL1 Q9Y468 1/20 0.66
LMNA P02545 1/20 0.31
HPGD P15428 1/20 0.31
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlorpyrifos SCHEMBL1069405 0.86 ALDH1A1 (0.89) TDP1MEN1KMT2ACYP3A4HSD17B10
Chlorpyrifos-Methyl SCHEMBL21647865 0.82 TDP1 (1.00) TDP1MEN1KMT2ACYP3A4HSD17B10
Chlorpyrifos-Methyl SCHEMBL27546 0.82 TDP1 (1.00) TDP1MEN1KMT2ACYP3A4HSD17B10
Chlorpyrifos SCHEMBL9320084 0.81 TDP1 (0.74) TDP1MEN1KMT2ACYP3A4HSD17B10
Chlorpyrifos SCHEMBL7908295 0.80 ALDH1A1 (1.00) TDP1MEN1KMT2ACYP3A4HSD17B10
Chlorpyrifos SCHEMBL21680 0.80 ALDH1A1 (1.00) TDP1MEN1KMT2ACYP3A4HSD17B10
Chlorpyrifos SCHEMBL28566223 0.79 ALDH1A1 (0.97) TDP1MEN1KMT2ACYP3A4HSD17B10
Chlorpyrifos SCHEMBL18228939 0.79 ALDH1A1 (0.97) TDP1MEN1KMT2ACYP3A4HSD17B10
Chlorpyrifos SCHEMBL29011072 0.79 ALDH1A1 (0.97) TDP1MEN1KMT2ACYP3A4HSD17B10
Chlorpyrifos SCHEMBL28945660 0.79 ALDH1A1 (0.97) TDP1MEN1KMT2ACYP3A4HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021002484-A9 HERBICIDE AND PRODUCTION METHOD FOR INTERMEDIATE THEREOF クミアイ化学工業株式会社 2021-04-15 WO disclosed