Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 8/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14998290 | 0.93 | MAPT (0.46) | TDP1POLBHTTAPEX1MAPT | |
| SCHEMBL4253388 | 0.88 | MAPT (0.47) | MAOATDP1POLBMAPTMAPK1 | |
| SCHEMBL26937995 | 0.85 | MAPT (0.44) | MAOATDP1POLBMAPTMAPK1 | |
| SCHEMBL2840293 | 0.85 | MAOA (0.51) | MAOATDP1POLBHTTMAPT | |
| SCHEMBL23213500 | 0.84 | MAOA (0.43) | MAOATDP1POLBHTTMAPT | |
| SCHEMBL10581861 | 0.81 | KCNA3 (0.51) | MAOATDP1POLBHTTMAPT | |
| SCHEMBL2840055 | 0.81 | MAOA (0.45) | MAOATDP1MAPTMAPK1L3MBTL1 | |
| SCHEMBL261845 | 0.81 | MAPT (0.55) | TDP1POLBHTTMAPTMAPK1 | |
| SCHEMBL29462117 | 0.81 | MAPT (0.55) | TDP1POLBHTTMAPTMAPK1 | |
| SCHEMBL2840051 | 0.79 | MAOA (0.52) | MAOATDP1POLBHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12552891-B2 | Non-degradable embolisation microsphere | GUERBET (FR) | 2026-02-17 | — | — | US | disclosed |
| CN-119219832-A | Non-degradable radiopaque embolic microspheres | 法国加栢 | 2024-12-31 | — | — | CN | disclosed |
| CN-114555659-B | Non-degradable radiopaque embolic microspheres | 法国加栢 | 2024-09-20 | — | — | CN | disclosed |
| US-20230285601-A1 | NON DEGRADABLE RADIO-OPAQUE EMBOLISATION MICROSPHERE | GUERBET (FR) | 2023-09-14 | — | — | US | disclosed |
| US-20230285601-A1 | NON DEGRADABLE RADIO-OPAQUE EMBOLISATION MICROSPHERE | GUERBET (FR) | 2023-09-14 | — | — | US | disclosed |
| US-20230272142-A1 | NON-DEGRADABLE EMBOLISATION MICROSPHERE | GUERBET (FR) | 2023-08-31 | — | — | US | disclosed |
| US-20230272142-A1 | NON-DEGRADABLE EMBOLISATION MICROSPHERE | GUERBET (FR) | 2023-08-31 | — | — | US | disclosed |
| US-20230272142-A1 | NON-DEGRADABLE EMBOLISATION MICROSPHERE | GUERBET (FR) | 2023-08-31 | — | — | US | disclosed |
| EP-4041319-A1 | NON DEGRADABLE RADIO-OPAQUE EMBOLISATION MICROSPHERE | Guerbet (FR) | 2022-08-17 | — | — | EP | disclosed |
| EP-4041318-A1 | NON-DEGRADABLE EMBOLISATION MICROSPHERE | Guerbet (FR) | 2022-08-17 | — | — | EP | disclosed |
| CN-114555139-A | Non-degradable embolic microspheres | 法国加栢 | 2022-05-27 | — | — | CN | disclosed |
| CN-114555659-A | Nondegradable radiopaque embolic microspheres | 法国加栢 | 2022-05-27 | — | — | CN | disclosed |
| WO-2021069528-A1 | NON DEGRADABLE RADIO-OPAQUE EMBOLISATION MICROSPHERE | GUERBET (FR) | 2021-04-15 | — | — | WO | disclosed |
| WO-2021069527-A1 | NON-DEGRADABLE EMBOLISATION MICROSPHERE | GUERBET (FR) | 2021-04-15 | — | — | WO | disclosed |
| WO-2021069527-A1 | NON-DEGRADABLE EMBOLISATION MICROSPHERE | GUERBET (FR) | 2021-04-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12552891-B2 | Non-degradable embolisation microsphere | VEGFA, FGB, MSR1 | MAOA 1175/4885TDP1 3758/4885POLB 534/4885 |
| US-20230285601-A1 | NON DEGRADABLE RADIO-OPAQUE EMBOLISATION MICROSPHERE | KIT, TIE1, HRH4 | MAOA 1335/4885TDP1 2001/4885POLB 1251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.