Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MITF | O75030 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | SDCBP | O00560 | 1/20 | 0.55 |
| ▸ | SDC2 | P34741 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.51 |
| ▸ | YAP1 | P46937 | 1/20 | 0.51 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.51 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15426813 | 0.85 | ALDH1A1 (0.50) | HPGDHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL5656305 | 0.83 | RAB9A (0.49) | HPGDHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL11870523 | 0.81 | SMN1; SMN2 (0.65) | HPGDALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL11870623 | 0.81 | HPGD (0.61) | HPGDHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL28117136 | 0.81 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2AHTTTDP1 | |
| SCHEMBL10717383 | 0.81 | CYP1A2 (0.68) | HPGDHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL11867961 | 0.81 | ALDH1A1 (0.48) | HPGDHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL11872394 | 0.81 | HPGD (0.51) | HPGDHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL1224206 | 0.80 | TRPM5 (0.50) | HPGDHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL11863116 | 0.79 | ALDH1A1 (0.49) | HPGDALDH1A1MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130065962-A1 | Compounds For Use In The Treatment Of Diseases | INOXIA LIFESCIENCES GMBH (AT) | 2013-03-14 | — | — | US | claimed |
| CN-102858329-A | Compounds for the treatment of diseases | PLANTA NATURSTOFFE VERTRIEBSGES M B H | 2013-01-02 | — | — | CN | claimed |
| EP-2528595-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF DISEASES | Inoxia Lifesciences GmbH (AT) | 2012-12-05 | — | — | EP | claimed |
| WO-2011091461-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF DISEASES | PLANTA NATURSTOFFE VERTRIEBSGES.M.B.H. (AT) | 2011-08-04 | — | — | WO | claimed |
| CN-106632129-B | The double thioether analog derivative, preparation method and application of (thiophene) diazole are disliked containing 1,3,4- | 贵州大学 | 2019-06-07 | — | — | CN | disclosed |
| CN-106167472-B | A kind of 2,5- substituent groups -1,3,4- oxadiazole double thioethers analog derivative, preparation method and application | 贵州大学 | 2018-07-27 | — | — | CN | disclosed |
| CN-106632129-A | Disulfide derivative containing 1,3,4-oxa(thia)diazole and preparation method and application of derivative | 贵州大学 | 2017-05-10 | — | — | CN | disclosed |
| CN-106167472-A | A kind of 2,5 substituent group 1,3,4 diazole thioether analog derivatives, its preparation method and application | 贵州大学 | 2016-11-30 | — | — | CN | disclosed |
| EP-2965755-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF DISEASES | Inoxia Lifesciences GmbH (AT) | 2016-01-13 | — | — | EP | disclosed |
| EP-2965755-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF DISEASES | Inoxia Lifesciences GmbH (AT) | 2016-01-13 | — | — | EP | disclosed |
| CN-104958286-A | Compounds for use in the treatment of diseases | INOXIA LIFESCIENCES GMBH | 2015-10-07 | — | — | CN | disclosed |
| CN-102858329-B | Compounds for the treatment of diseases | INOXIA LIFESCIENCES GMBH | 2015-06-17 | — | — | CN | disclosed |
| US-20130065962-A1 | Compounds For Use In The Treatment Of Diseases | INOXIA LIFESCIENCES GMBH (AT) | 2013-03-14 | — | — | US | disclosed |
| US-20130065962-A1 | Compounds For Use In The Treatment Of Diseases | INOXIA LIFESCIENCES GMBH (AT) | 2013-03-14 | — | — | US | disclosed |
| US-20130065962-A1 | Compounds For Use In The Treatment Of Diseases | INOXIA LIFESCIENCES GMBH (AT) | 2013-03-14 | — | — | US | disclosed |
| CN-102858329-A | Compounds for the treatment of diseases | PLANTA NATURSTOFFE VERTRIEBSGES M B H | 2013-01-02 | — | — | CN | disclosed |
| EP-2528595-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF DISEASES | Inoxia Lifesciences GmbH (AT) | 2012-12-05 | — | — | EP | disclosed |
| WO-2011091461-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF DISEASES | PLANTA NATURSTOFFE VERTRIEBSGES.M.B.H. (AT) | 2011-08-04 | — | — | WO | disclosed |
| US-3972905-A | FUNGICIDE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130065962-A1 | Compounds For Use In The Treatment Of Diseases | SLC10A1, CYP27A1, OAT | HPGD 401/4885HSD17B10 458/4885ALDH1A1 353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.