SCHEMBL2321360

SCHEMBL2321360

Cc1cccc(Nc2cccc3ccccc23)c1C

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.55
TP53 P04637 3/20 0.55
CYP3A4 P08684 2/20 0.55
TSHR P16473 2/20 0.55
CDC25B P30305 2/20 0.55
HPGD P15428 2/20 0.55
ALOX15 P16050 1/20 0.55
ATM Q13315 1/20 0.55
HSD17B10 Q99714 1/20 0.55
CYP2A6 P11509 2/20 0.54
MEN1 O00255 3/20 0.53
KMT2A Q03164 3/20 0.53
CYP1A2 P05177 2/20 0.53
LMNA P02545 2/20 0.53
AKR1B10 O60218 1/20 0.53
TRPA1 O75762 1/20 0.53
ABCB11 O95342 1/20 0.53
DHFR P00374 1/20 0.53
MPO P05164 1/20 0.53
CHRM1 P11229 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1010313 0.88 ALDH1A1 (0.59) ALDH1A1TP53CYP3A4TSHRCDC25B
SCHEMBL21515414 0.85 ALDH1A1 (0.55) ALDH1A1TP53CYP3A4TSHRCDC25B
SCHEMBL1922753 0.83 LMNA (0.63) ALDH1A1TP53CYP3A4TSHRHPGD
SCHEMBL4189645 0.83 RAPGEF4 (0.65) ALDH1A1CYP3A4HPGDALOX15HSD17B10
SCHEMBL49213 0.83 HSD17B10 (0.74) ALDH1A1TP53CYP3A4TSHRCDC25B
SCHEMBL11403543 0.81 KMT2A (0.61) ALDH1A1TP53CYP3A4HPGDALOX15
SCHEMBL1921580 0.81 HSD17B10 (0.71) ALDH1A1TP53CYP3A4TSHRCDC25B
Ammonia Solution, Strong SCHEMBL11586421 0.81 HSD17B10 (0.71) ALDH1A1TP53CYP3A4TSHRCDC25B
SCHEMBL8500339 0.81 HSD17B10 (0.71) ALDH1A1TP53CYP3A4TSHRCDC25B
SCHEMBL20717964 0.79 ALDH1A1 (0.63) ALDH1A1TP53CYP3A4TSHRCDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108034478-A The special antioxidant mixture of automobile gear oil 中国第汽车股份有限公司 2018-05-15 CN disclosed
EP-1899289-B1 METHOD FOR PRODUCING ARYL AMINES, ARYL ETHERS AND ARYL THIOETHERS ARCHIMICA GMBH (DE) 2011-08-10 EP disclosed
US-20080306260-A1 Method for Producing Aryl Amines, Aryl Ethers and Aryl Thioethers ARCHIMICA GMBH (DE) 2008-12-11 US disclosed
EP-1899289-A1 METHOD FOR PRODUCING ARYL AMINES, ARYL ETHERS AND ARYL THIOETHERS Archimica GmbH (DE) 2008-03-19 EP disclosed
US-7303856-B2 Light-sensitive sheet comprising support, first light-sensitive layer and second light-sensitive layer FUJIFILM CORPORATION (JP) 2007-12-04 US disclosed
WO-2007071345-A1 SULFONATED PHOSPHINE LIGANDS AND PROCESS FOR CROSS-COUPLING ARYL HALIDES AND ARYLSULFONATES AND HETEROARYL HALIDES AND HETEROARYLSULFONATES WITH AMINES, ALCOHOLS AND CARBON NUCLEOPHILES BY USING THE LIGANDS IN CONJUNCTION WITH TRANSITION METAL CATALYSTS ARCHIMICA GMBH (DE) 2007-06-28 WO disclosed
WO-2007000250-A1 METHOD FOR PRODUCING ARYL AMINES, ARYL ETHERS AND ARYL THIOETHERS ARCHIMICA GMBH (DE) 2007-01-04 WO disclosed
US-7150955-B2 Light-sensitive sheet comprising support, first and second light-sensitive layers and barrier layer FUJI PHOTO FILM CO., LTD. (JP) 2006-12-19 US disclosed
US-20050037281-A1 Light-sensitive sheet comprising support, first and second light-sensitive layers and barrier layer FUJI PHOTO FILM CO., LTD. 2005-02-17 US disclosed
EP-1507171-A2 Light-Sensitive sheet comprising support, first and second light-sensitive layers and barrier layer FUJI PHOTO FILM CO., LTD. (JP) 2005-02-16 EP disclosed
US-20050025946-A1 Light-sensitive sheet comprising support, first light-sensitive layer and second light-sensitive layer FUJI PHOTO FILM CO., LTD. 2005-02-03 US disclosed
EP-1489460-A2 Light-sensitive sheet comprising support, first light-sensitive layer and second light-sensitive layer Fuji Photo Film Co., Ltd. (JP) 2004-12-22 EP disclosed
US-4394279-A Antioxidant combinations of sulfur containing molybdenum complexes and aromatic amine compounds for lubricating oils CHEVRON RESEARCH COMPANY (US) 1983-07-19 US disclosed
US-4370246-A Antioxidant combinations of molybdenum complexes and aromatic amine compounds CHEVRON RESEARCH COMPANY (US) 1983-01-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080306260-A1 Method for Producing Aryl Amines, Aryl Ethers and Aryl Thioethers TST, TAAR1, TSHR ALDH1A1 1524/4885TP53 2461/4885CYP3A4 718/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.