Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GRN | P28799 | 1/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | RPA1 | P27694 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL574266 | 0.81 | NPC1 (0.60) | ALDH1A1NPC1RAB9AHCAR3HCAR2 | |
| SCHEMBL12321735 | 0.78 | ALDH1A1 (0.41) | ALDH1A1NPC1RAB9AHCAR3HCAR2 | |
| SCHEMBL2321521 | 0.78 | ALDH1A1 (0.41) | ALDH1A1NPC1RAB9AHCAR3HCAR2 | |
| SCHEMBL950878 | 0.77 | ALDH1A1 (0.46) | ALDH1A1NPC1RAB9AKDM4EPOLB | |
| SCHEMBL12321704 | 0.77 | ALDH1A1 (0.40) | ALDH1A1NPC1RAB9AHCAR3HCAR2 | |
| SCHEMBL4011177 | 0.74 | RPA1 (0.58) | ALDH1A1NPC1RAB9AKDM4ERPA1 | |
| SCHEMBL12321739 | 0.74 | HCAR2 (0.41) | ALDH1A1NPC1RAB9AHCAR3HCAR2 | |
| SCHEMBL12321714 | 0.74 | PLAT (0.40) | ALDH1A1NPC1RAB9AHCAR3HCAR2 | |
| SCHEMBL2152111 | 0.74 | HCAR2 (0.41) | ALDH1A1HCAR3HCAR2DAOKDM4E | |
| SCHEMBL18358740 | 0.72 | RPA1 (0.44) | ALDH1A1NPC1RAB9AKDM4ERPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2826772-A1 | Intermediates for the synthesis of oxygen-substituted 3-heteroaroylamino-propionic acid derivatives | SANOFI (FR) | 2015-01-21 | — | — | EP | disclosed |
| EP-2528902-B1 | OXYGEN-SUBSTITUTED 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2014-11-12 | — | — | EP | disclosed |
| US-20140128616-A1 | OXYGEN-SUBSTITUTED 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2014-05-08 | — | — | US | disclosed |
| US-8664257-B2 | Oxygen-substituted 3-heteroaroylamino-propionic acid derivatives and their use as pharmaceuticals | SANOFI (FR) | 2014-03-04 | — | — | US | disclosed |
| US-20130046004-A1 | OXYGEN-SUBSTITUTED 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2013-02-21 | — | — | US | disclosed |
| EP-2528902-A1 | OXYGEN-SUBSTITUTED 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2012-12-05 | — | — | EP | disclosed |
| WO-2011092187-A1 | OXYGEN-SUBSTITUTED 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2011-08-04 | — | — | WO | disclosed |
| US-7704310-B2 | Trisazo-dyes with a pyrazolyl end group and their use in ink-jet printing | FUJIFILM IMAGING COLORANTS LIMITED (GB) | 2010-04-27 | — | — | US | disclosed |
| US-7704310-B2 | Trisazo-dyes with a pyrazolyl end group and their use in ink-jet printing | FUJIFILM IMAGING COLORANTS LIMITED (GB) | 2010-04-27 | — | — | US | disclosed |
| US-20100015411-A1 | Trisazo-dyes with a Pyrazolyl End Group and Their Use in Ink-jet Printing | FUJIFILM IMAGING COLORANTS LIMITED (GB) | 2010-01-21 | — | — | US | disclosed |
| US-20100015411-A1 | Trisazo-dyes with a Pyrazolyl End Group and Their Use in Ink-jet Printing | FUJIFILM IMAGING COLORANTS LIMITED (GB) | 2010-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130046004-A1 | OXYGEN-SUBSTITUTED 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | CTSF, CTSS, CTSE | ALDH1A1 581/4885NPC1 1157/4885RAB9A 633/4885 |
| US-20140128616-A1 | OXYGEN-SUBSTITUTED 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | CTSF, CTSS, CTSE | ALDH1A1 581/4885NPC1 1157/4885RAB9A 633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.