Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23229241 | 0.88 | HSD17B10 (0.59) | HSD17B10MTNR1AMTNR1BKDM4EPTGS1 | |
| SCHEMBL17967503 | 0.88 | HSD17B10 (0.77) | HSD17B10MTNR1AMTNR1BKDM4EPTGS1 | |
| SCHEMBL30831943 | 0.87 | HSD17B10 (0.75) | HSD17B10KDM4EPTGS1AKR1C3AKR1C2 | |
| SCHEMBL1097902 | 0.87 | HSD17B10 (0.75) | HSD17B10KDM4EPTGS1AKR1C3AKR1C2 | |
| Hydrochloric Acid SCHEMBL2527027 | 0.85 | HSD17B10 (0.73) | HSD17B10KDM4EPTGS1AKR1C3AKR1C2 | |
| SCHEMBL23228992 | 0.85 | MTNR1A (0.49) | HSD17B10MTNR1AMTNR1BKDM4EPOLB | |
| SCHEMBL24075695 | 0.83 | APLNR (0.50) | HSD17B10MTNR1AMTNR1BKDM4EKMT2A | |
| Acetic Acid SCHEMBL27488564 | 0.83 | MTNR1A (0.50) | HSD17B10MTNR1AMTNR1BKDM4EPOLB | |
| SCHEMBL5122876 | 0.82 | MTNR1A (0.57) | HSD17B10MTNR1AMTNR1BKDM4EPOLB | |
| SCHEMBL24200358 | 0.81 | HSD17B10 (0.55) | HSD17B10MTNR1AMTNR1BKDM4EPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3687506-B1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | BIOCRYST PHARM INC (US) | 2021-07-07 | — | — | EP | disclosed |
| WO-2021072198-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |