Acetic Acid

Acetic Acid

SCHEMBL27488564

CC(=O)O.CCOc1cc(OC)ccc1CO

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 1/20 0.50
MTNR1B P49286 1/20 0.50
KDM4E B2RXH2 2/20 0.48
HSD17B10 Q99714 2/20 0.45
TSHR P16473 4/20 0.44
POLB P06746 1/20 0.43
MAPT P10636 2/20 0.43
LMNA P02545 1/20 0.43
HPGD P15428 1/20 0.43
ATM Q13315 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
MAPK1 P28482 1/20 0.43
CYP3A4 P08684 1/20 0.42
ATP4A P20648 1/20 0.42
ATP4B P51164 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
TAS1R3 Q7RTX0 1/20 0.41
TAS1R1 Q7RTX1 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23229043 0.83 HSD17B10 (0.62) MTNR1AMTNR1BKDM4EHSD17B10TSHR
SCHEMBL24075695 0.82 APLNR (0.50) MTNR1AMTNR1BKDM4EHSD17B10TSHR
SCHEMBL6784748 0.82 KDM4E (0.53) KDM4EHSD17B10TSHRMAPTLMNA
SCHEMBL8900829 0.81 PTPN1 (0.51) KDM4EHSD17B10TSHRPOLBMAPT
SCHEMBL16046624 0.80 HSD17B10 (0.49) HSD17B10POLBSMN1; SMN2TAS1R3TAS1R1
SCHEMBL20436807 0.79 IDO1 (0.42) KDM4EHSD17B10
SCHEMBL16950704 0.79 MTNR1A (0.56) MTNR1AMTNR1BKDM4EHSD17B10TSHR
SCHEMBL6492912 0.79 APLNR (0.47) KDM4ETSHRMAPTMAPK1TAS1R3
SCHEMBL238087 0.78 APLNR (0.63) KDM4EHSD17B10MAPTCYP3A4
SCHEMBL23228992 0.78 MTNR1A (0.49) MTNR1AMTNR1BKDM4EHSD17B10POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1198861-C Process for producing polyurethane foamed plastic CK WAIGHTKE CO (US) 2005-04-27 CN claimed
CN-1267674-A Process for producing polyurethane foamed plastic CK WAIGHTKE CO (US) 2000-09-27 CN claimed
CN-1198861-C Process for producing polyurethane foamed plastic CK WAIGHTKE CO (US) 2005-04-27 CN disclosed
CN-1267674-A Process for producing polyurethane foamed plastic CK WAIGHTKE CO (US) 2000-09-27 CN disclosed