Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2323797 | 0.81 | ADRB1 (0.55) | ALDH1A1KDM4ELMNA | |
| SCHEMBL3243008 | 0.79 | ADRA1B (0.45) | SMN1; SMN2ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL2321072 | 0.76 | DRD4 (0.49) | SMN1; SMN2ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL23161511 | 0.76 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1TSHRHSD17B10KDM4E | |
| SCHEMBL3042980 | 0.76 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1TSHRHSD17B10KDM4E | |
| SCHEMBL2325942 | 0.76 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1TSHRHSD17B10KDM4E | |
| SCHEMBL8698562 | 0.75 | SMN1; SMN2 (0.69) | SMN1; SMN2ALDH1A1TSHRHSD17B10KDM4E | |
| SCHEMBL21361444 | 0.75 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1TSHRHSD17B10KDM4E | |
| SCHEMBL1372296 | 0.75 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1TSHRHSD17B10KDM4E | |
| SCHEMBL735202 | 0.75 | ALDH1A1 (0.61) | SMN1; SMN2ALDH1A1TSHRHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |