Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.63 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.63 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.63 |
| ▸ | CPB1 | P15086 | 1/20 | 0.60 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.60 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.54 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.54 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.54 |
| ▸ | CTSL | P07711 | 2/20 | 0.53 |
| ▸ | TLR2 | O60603 | 2/20 | 0.53 |
| ▸ | KLK7 | P49862 | 1/20 | 0.52 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 1/20 | 0.52 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.52 |
| ▸ | CHRNG | P07510 | 1/20 | 0.52 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.52 |
| ▸ | CHRND | Q07001 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18072615 | 0.89 | CTSL (0.61) | SIRT2SIRT1SIRT3PSMB8PSMB9 | |
| SCHEMBL20653746 | 0.89 | CTSL (0.67) | SIRT2PSMB8PSMB9PSMB5CTSL | |
| SCHEMBL19933134 | 0.89 | PTGER4 (0.57) | SIRT2SIRT1CPB1CPB2PSMB8 | |
| SCHEMBL17039853 | 0.89 | FOLH1 (0.57) | SIRT2SIRT1CPB1CPB2PSMB8 | |
| SCHEMBL12148814 | 0.89 | MAPT (0.62) | SIRT2SIRT1SIRT3CPB1CPB2 | |
| SCHEMBL24234635 | 0.89 | CPB1 (0.59) | SIRT2SIRT1SIRT3CPB1CPB2 | |
| SCHEMBL23626336 | 0.88 | CPB1 (0.67) | SIRT2SIRT1SIRT3CPB1CPB2 | |
| SCHEMBL23446339 | 0.88 | CPB1 (0.57) | SIRT2SIRT1SIRT3CPB1CPB2 | |
| SCHEMBL30902797 | 0.87 | MAPT (0.62) | SIRT2SIRT1SIRT3CPB1CPB2 | |
| SCHEMBL13785523 | 0.87 | SIRT2 (0.71) | SIRT2SIRT1SIRT3CPB1CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11828752-B2 | Protease-activated contrast agents for in vivo imaging | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2023-11-28 | — | — | US | disclosed |
| US-20210109090-A1 | PROTEASE-ACTIVATED CONTRAST AGENTS FOR IN VIVO IMAGING | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2021-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210109090-A1 | PROTEASE-ACTIVATED CONTRAST AGENTS FOR IN VIVO IMAGING | CTSV, CTSF, CTSS | SIRT2 4119/4885SIRT1 4282/4885SIRT3 4639/4885 |
| US-11828752-B2 | Protease-activated contrast agents for in vivo imaging | CTSV, CTSF, CTSS | SIRT2 4119/4885SIRT1 4282/4885SIRT3 4639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.