Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.31 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23361234 | 0.83 | NPC1 (0.43) | NPC1RAB9ASLC5A2MEN1KMT2A | |
| SCHEMBL23370326 | 0.82 | ADORA2A (0.35) | KDRMAPK14TNNI3KALDH1A1 | |
| SCHEMBL23370324 | 0.80 | ALDH1A1 (0.34) | KDRMAPK14TNNI3KALDH1A1 | |
| SCHEMBL24854026 | 0.76 | NPC1 (0.37) | NPC1RAB9ASLC5A2POLBMEN1 | |
| SCHEMBL29808506 | 0.71 | KDR (0.36) | NPC1RAB9AKDRMAPK14TNNI3K | |
| SCHEMBL23247716 | 0.71 | KDR (0.36) | NPC1RAB9AKDRMAPK14TNNI3K | |
| SCHEMBL24786607 | 0.71 | SCN9A (0.36) | KDRMAPK14TNNI3KPOLBALDH1A1 | |
| SCHEMBL23370307 | 0.70 | NPC1 (0.36) | NPC1RAB9ASLC5A2MEN1KMT2A | |
| SCHEMBL24854151 | 0.70 | KCNMA1 (0.38) | NPC1RAB9AMEN1KMT2ASLC9A1 | |
| SCHEMBL12825945 | 0.64 | KEAP1 (0.51) | NPC1RAB9AKDRMAPK14TNNI3K |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002357-A1 | 7-PYRIMIDINE-2-YL-OXY-INDAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA CROP PROTECTION AG (CH) | 2023-01-05 | — | — | US | disclosed |
| WO-2021094416-A1 | 7-PYRIMIDINE-2-YL-OXY-INDAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA CROP PROTECTION AG (CH) | 2021-05-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002357-A1 | 7-PYRIMIDINE-2-YL-OXY-INDAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | AZI2, PDXK, DPYD | NPC1 4415/4885RAB9A 2838/4885SLC5A2 781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.