Sugi Predict

Sugi Predict / Compounds / SCHEMBL1769607

SCHEMBL1769607

SCHEMBL1769607

N[C@@H](CCc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 4/20 0.74
▸ MEN1 O00255 4/20 0.74
▸ KMT2A Q03164 4/20 0.74
▸ KDM4E B2RXH2 3/20 0.74
▸ MPO P05164 2/20 0.74
▸ PMP22 Q01453 2/20 0.74
▸ LMNA P02545 2/20 0.74
▸ TSHR P16473 2/20 0.74
▸ BLM P54132 2/20 0.74
▸ HIF1A Q16665 1/20 0.74
▸ SMN1; SMN2 Q16637 2/20 0.58
▸ APAF1 O14727 1/20 0.57
▸ POLB P06746 1/20 0.57
▸ RECQL P46063 1/20 0.57
▸ L3MBTL1 Q9Y468 1/20 0.57
▸ ALDH1A1 P00352 3/20 0.56
▸ GAA P10253 1/20 0.56
▸ CYP1A2 P05177 3/20 0.55
▸ CYP3A4 P08684 2/20 0.55
▸ CYP2D6 P10635 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1769610 1.00 MAPT (0.74) MAPTMEN1KMT2AKDM4EMPO
SCHEMBL29414366 1.00 MAPT (0.74) MAPTMEN1KMT2AKDM4EMPO
SCHEMBL27426182 1.00 MAPT (0.74) MAPTMEN1KMT2AKDM4EMPO
SCHEMBL17704081 0.92 KDM4E (0.70) MAPTMEN1KMT2AKDM4EMPO
SCHEMBL23897642 0.87 MAPT (0.59) MAPTMEN1KMT2AKDM4EMPO
SCHEMBL26428319 0.86 HTR2A (0.60) MAPTMEN1KMT2AKDM4EMPO
SCHEMBL23762398 0.86 HTR2A (0.60) MAPTMEN1KMT2AKDM4EMPO
Tryptophan SCHEMBL4732053 0.85 KMT2A (1.00) MAPTMEN1KMT2AKDM4EMPO
Dl-Tryptophan SCHEMBL475349 0.85 KMT2A (1.00) MAPTMEN1KMT2AKDM4EMPO
Tryptophan SCHEMBL23141133 0.85 KMT2A (1.00) MAPTMEN1KMT2AKDM4EMPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2024-12-05 — — US claimed
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2024-12-05 — — US disclosed
US-11753446-B2 Beta-hairpin peptidomimetics POLYPHOR AG (CH) 2023-09-12 — — US disclosed
US-11629171-B2 Beta-hairpin peptidomimetics SPEXIS AG (CH) 2023-04-18 — — US disclosed
CN-115093463-A Beta-hairpin peptidomimetics 波利弗尔股份公司 2022-09-23 — — CN disclosed
EP-3201219-B1 BETA-HAIRPIN PEPTIDOMIMETICS POLYPHOR AG (CH) 2021-11-17 — — EP disclosed
EP-3201218-B1 BETA-HAIRPIN PEPTIDOMIMETICS POLYPHOR AG (CH) 2021-11-03 — — EP disclosed
CN-105324390-B Beta-hairpin peptidomimetics 波利弗尔股份公司 2021-10-19 — — CN disclosed
US-20210284693-A1 BETA-HAIRPIN PEPTIDOMIMETICS SPEXIS AG (CH) 2021-09-16 — — US disclosed
US-20210155771-A1 PLASTICIZER AND PLASTIC PRODUCT LARGAN MEDICAL CO., LTD. (TW) 2021-05-27 — — US disclosed
CN-105324390-A Beta-hairpin peptidomimetics POLYPHOR AG 2016-02-10 — — CN disclosed
US-20150307556-A1 TEMPLATE-FIXED PEPTIDOMIMETICS WITH CXCR7 MODULATING ACTIVITY POLYPHOR AG (CH) 2015-10-29 — — US disclosed
US-9109009-B2 Template-fixed peptidomimetics with CXCR7 modulating activity POLYPHOR AG (CH) 2015-08-18 — — US disclosed
US-20140287986-A1 TEMPLATE-FIXED PEPTIDOMIMETICS AS INHIBITORS OF FPR1 POLYPHOR AG (CH) 2014-09-25 — — US disclosed
US-8754038-B2 Template-fixed peptidomimetics with CCR10 antagonistic activity POLYPHOR AG (CH) 2014-06-17 — — US disclosed
US-20130225506-A1 TEMPLATE-FIXED PEPTIDOMIMETICS WITH CXCR7 MODULATING ACTIVITY POLYPHOR AG (CH) 2013-08-29 — — US disclosed
CN-102844327-A Template-fixed peptidomimetics with CXCR7 modulatory activity POLYPHOR AG 2012-12-26 — — CN disclosed
US-20120283168-A1 TEMPLATE-FIXED PEPTIDOMIMETICS WITH CCR10 ANTAGONISTIC ACTIVITY POLYPHOR AG (CH) 2012-11-08 — — US disclosed
CN-102712676-A Template-fixed peptidomimetics with CCR10 antagonistic activty POLYPHOR AG 2012-10-03 — — CN disclosed
WO-2011060832-A1 TEMPLATE-FIXED PEPTIDOMIMETICS WITH CCR10 ANTAGONISTIC ACTIVITY POLYPHOR AG (CH) 2011-05-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140287986-A1 TEMPLATE-FIXED PEPTIDOMIMETICS AS INHIBITORS OF FPR1 FPR1, FPR3, FPR2 MAPT 2455/4885MEN1 3931/4885KMT2A 4684/4885
US-20120283168-A1 TEMPLATE-FIXED PEPTIDOMIMETICS WITH CCR10 ANTAGONISTIC ACTIVITY CCR10, CCR1, CCRL2 MAPT 3273/4885MEN1 3852/4885KMT2A 3431/4885
US-20150307556-A1 TEMPLATE-FIXED PEPTIDOMIMETICS WITH CXCR7 MODULATING ACTIVITY CXCR1, CXCL12, CXCR6 MAPT 4808/4885MEN1 3558/4885KMT2A 4208/4885
US-11629171-B2 Beta-hairpin peptidomimetics POLL, POLQ, HBZ MAPT 3326/4885MEN1 2209/4885KMT2A 2109/4885
US-20130225506-A1 TEMPLATE-FIXED PEPTIDOMIMETICS WITH CXCR7 MODULATING ACTIVITY CXCR1, CXCL12, CXCR6 MAPT 4798/4885MEN1 3757/4885KMT2A 4121/4885
US-20210284693-A1 BETA-HAIRPIN PEPTIDOMIMETICS POLL, POLQ, POLM MAPT 3771/4885MEN1 2007/4885KMT2A 1715/4885
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES BCAT1, BCAT2, PELP1 MAPT 1809/4885MEN1 4354/4885KMT2A 3415/4885
US-11753446-B2 Beta-hairpin peptidomimetics POLL, BACE1, C1S MAPT 2235/4885MEN1 745/4885KMT2A 2961/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.