SCHEMBL29414366

SCHEMBL29414366

N[C@@H](CCc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.74
MEN1 O00255 4/20 0.74
KMT2A Q03164 4/20 0.74
KDM4E B2RXH2 3/20 0.74
MPO P05164 2/20 0.74
PMP22 Q01453 2/20 0.74
LMNA P02545 2/20 0.74
TSHR P16473 2/20 0.74
BLM P54132 2/20 0.74
HIF1A Q16665 1/20 0.74
SMN1; SMN2 Q16637 2/20 0.58
APAF1 O14727 1/20 0.57
POLB P06746 1/20 0.57
RECQL P46063 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
ALDH1A1 P00352 3/20 0.56
GAA P10253 1/20 0.56
CYP1A2 P05177 3/20 0.55
CYP3A4 P08684 2/20 0.55
CYP2D6 P10635 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1769607 1.00 MAPT (0.74) MAPTMEN1KMT2AKDM4EMPO
SCHEMBL1769610 1.00 MAPT (0.74) MAPTMEN1KMT2AKDM4EMPO
SCHEMBL27426182 1.00 MAPT (0.74) MAPTMEN1KMT2AKDM4EMPO
SCHEMBL17704081 0.92 KDM4E (0.70) MAPTMEN1KMT2AKDM4EMPO
SCHEMBL23897642 0.87 MAPT (0.59) MAPTMEN1KMT2AKDM4EMPO
SCHEMBL26428319 0.86 HTR2A (0.60) MAPTMEN1KMT2AKDM4EMPO
SCHEMBL23762398 0.86 HTR2A (0.60) MAPTMEN1KMT2AKDM4EMPO
Tryptophan SCHEMBL4732053 0.85 KMT2A (1.00) MAPTMEN1KMT2AKDM4EMPO
Dl-Tryptophan SCHEMBL475349 0.85 KMT2A (1.00) MAPTMEN1KMT2AKDM4EMPO
Tryptophan SCHEMBL23141133 0.85 KMT2A (1.00) MAPTMEN1KMT2AKDM4EMPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 315 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12600699-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-14 US claimed
EP-4720087-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR Zealand Pharma A/S (DK) 2026-04-08 EP claimed
US-20250027949-A1 EVALUATING METHOD FOR RELATIVE PHARMACOLOGICAL ACTIONS OF COMBINATIONS OF IMMUNE CHECKPOINT INHIBITORS AND ANTICANCER DRUGS AS COMBINATION DRUGS COMPARED WITH PHARMACOLOGICAL ACTIONS OF IMMUNE CHECKPOINT INHIBITORS ALONE, CALCULATING METHOD, EVALUATING APPARATUS, CALCULATING APPARATUS, EVALUATING PROGRAM, CALCULATING PROGRAM, RECORDING MEDIUM, EVALUATING SYSTEM, AND TERMINAL APPARATUS AJINOMOTO CO., INC. (JP) 2025-01-23 US claimed
WO-2024246269-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR ZEALAND PHARMA A/S (DK) 2024-12-05 WO claimed
EP-4471048-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR Zealand Pharma A/S (DK) 2024-12-04 EP claimed
EP-4471049-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR Zealand Pharma A/S (DK) 2024-12-04 EP claimed
WO-2023195447-A1 EVALUATION METHOD, CALCULATION METHOD, EVALUATION DEVICE, CALCULATION DEVICE, EVALUATION PROGRAM, CALCULATION PROGRAM, RECORDING MEDIUM, EVALUATION SYSTEM AND TERMINAL DEVICE FOR RELATIVE PHARMACOLOGICAL ACTION OF COMBINATION OF IMMUNE CHECKPOINT INHIBITOR WITH ANTICANCER DRUG AS CONCOMITANT DRUG COMPARED TO PHARMACOLOGICAL ACTION OF IMMUNE CHECKPOINT INHIBITOR ALONE 味の素株式会社 2023-10-12 WO claimed
US-11753443-B2 Conjugated hepcidin mimetics PROTAGONIST THERAPEUTICS, INC. (US) 2023-09-12 US claimed
EP-4237427-A1 ANTIBACTERIAL CYCLOPEPTIDES TARGETING ACINETOBACTER AND OTHER GRAM-NEGATIVE PATHOGENS University of Utah Research Foundation (US) 2023-09-06 EP claimed
CN-116670151-A Antibacterial cyclic peptides targeting acinetobacter and other gram negative pathogens 犹他大学研究基金会 2023-08-29 CN claimed
EP-4188412-A1 CONJUGATED HEPCIDIN MIMETICS Protagonist Therapeutics, Inc. (US) 2023-06-07 EP claimed
CN-116178506-A Stapler peptide and application thereof 湖南中晟全肽生化有限公司 2023-05-30 CN claimed
US-20230111252-A1 THIOSEMICARBAZATES AND USES THEREOF THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2023-04-13 US claimed
WO-2022234972-A1 ANTIMICROBIAL PEPTOID HAVING IMPROVED SELECTIVITY AND ANTIMICROBIAL COMPOSITION COMPRISING SAME 광주과학기술원 2022-11-10 WO claimed
US-20220268790-A1 EVALUATING METHOD FOR PHARMACOLOGICAL ACTIONS OF IMMUNE CHECKPOINT INHIBITORS, CALCULATING METHOD, EVALUATING APPARATUS, CALCULATING APPARATUS, EVALUATING PROGRAM, CALCULATING PROGRAM, RECORDING MEDIUM, EVALUATING SYSTEM, AND TERMINAL APPARATUS AJINOMOTO CO., INC. (JP) 2022-08-25 US claimed
WO-2022094273-A1 ANTIBACTERIAL CYCLOPEPTIDES TARGETING ACINETOBACTER AND OTHER GRAM-NEGATIVE PATHOGENS UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2022-05-05 WO claimed
WO-2022026631-A1 CONJUGATED HEPCIDIN MIMETICS PROTAGONIST THERAPEUTICS, INC. (US) 2022-02-03 WO claimed
US-12612605-B2 Carboxyesterase polypeptides for kinetic resolution CODEXIS, INC. (US) 2026-04-28 US disclosed
WO-2022025204-A1 TREATMENT OF DISEASE WITH EPOR ANTAGONIST エポメッド株式会社 2022-02-03 WO disclosed
WO-2022026631-A1 CONJUGATED HEPCIDIN MIMETICS PROTAGONIST THERAPEUTICS, INC. (US) 2022-02-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11753443-B2 Conjugated hepcidin mimetics HAMP, VIP, HDGF MAPT 4733/4885MEN1 277/4885KMT2A 3691/4885
US-20230111252-A1 THIOSEMICARBAZATES AND USES THEREOF TST, ABAT, AADAC MAPT 1493/4885MEN1 850/4885KMT2A 1523/4885
US-12612605-B2 Carboxyesterase polypeptides for kinetic resolution CES1, CPA1, RNGTT MAPT 4855/4885MEN1 3279/4885KMT2A 1665/4885
US-12600699-B2 Thiosemicarbazates and uses thereof MET, THRB, ABAT MAPT 1679/4885MEN1 1699/4885KMT2A 2188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.