Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | NT5E | P21589 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CDC25A | P30304 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30013944 | 0.82 | ALDH1A1 (0.39) | ALDH1A1KMT2AKDM4EHSD17B10GAA | |
| SCHEMBL2631833 | 0.79 | ALDH1A1 (0.48) | ALDH1A1KDM4EHSD17B10GAAPOLB | |
| SCHEMBL11213802 | 0.79 | ALDH1A1 (0.52) | ALDH1A1KMT2AKDM4EHSD17B10GAA | |
| SCHEMBL29441612 | 0.79 | ALDH1A1 (0.52) | ALDH1A1KMT2AKDM4EHSD17B10GAA | |
| SCHEMBL21284339 | 0.77 | POLB (0.41) | ALDH1A1KMT2AKDM4EHSD17B10POLB | |
| SCHEMBL28759924 | 0.77 | ALDH1A1 (0.44) | ALDH1A1KMT2AKDM4EHSD17B10LMNA | |
| SCHEMBL9910017 | 0.76 | ALDH1A1 (0.46) | ALDH1A1KDM4EHSD17B10GAAPOLB | |
| SCHEMBL8577595 | 0.76 | ALDH1A1 (0.46) | ALDH1A1KDM4EHSD17B10GAAPOLB | |
| SCHEMBL13292304 | 0.75 | ALDH1A1 (0.44) | ALDH1A1KDM4EHSD17B10GAAPOLB | |
| SCHEMBL13302911 | 0.75 | POLB (0.45) | ALDH1A1KDM4EHSD17B10POLBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180000640-A1 | EYE TREATMENT | NICHAMIN LOUIS D (US) | 2018-01-04 | — | — | US | disclosed |
| US-9788994-B2 | Eye treatment | NICHAMIN LOUIS D (US) | 2017-10-17 | — | — | US | disclosed |
| US-20160235585-A1 | EYE TREATMENT | NICHAMIN LOUIS D (US) | 2016-08-18 | — | — | US | disclosed |
| US-20160074381-A1 | MODULATORS OF CELLULAR ADHESION | SARCODE BIOSCIENCE INC. (US) | 2016-03-17 | — | — | US | disclosed |
| US-9248126-B2 | Modulators of cellular adhesion | SARCODE BIOSCIENCE INC. (US) | 2016-02-02 | — | — | US | disclosed |
| US-9216174-B2 | Modulators of cellular adhesion | SARCODE BIOSCIENCE INC. (US) | 2015-12-22 | — | — | US | disclosed |
| US-8865232-B2 | Method for treating ocular Demodex | TISSUETECH, INC. (US) | 2014-10-21 | — | — | US | disclosed |
| US-8865232-B2 | Method for treating ocular Demodex | TISSUETECH, INC. (US) | 2014-10-21 | — | — | US | disclosed |
| US-8865232-B2 | Method for treating ocular Demodex | TISSUETECH, INC. (US) | 2014-10-21 | — | — | US | disclosed |
| US-20140066476-A1 | MODULATORS OF CELLULAR ADHESION | SARCODE BIOSCIENCE INC. (US) | 2014-03-06 | — | — | US | disclosed |
| US-20090214676-A1 | METHOD FOR TREATING OCULAR DEMODEX | TISSUETECH, INC. (US) | 2009-08-27 | — | — | US | disclosed |
| US-20090214676-A1 | METHOD FOR TREATING OCULAR DEMODEX | TISSUETECH, INC. (US) | 2009-08-27 | — | — | US | disclosed |
| US-20080182839-A1 | MODULATORS OF CELLULAR ADHESION | SUNESIS PHARMACEUTICALS, INC. (US) | 2008-07-31 | — | — | US | disclosed |
| US-20080176896-A1 | Modulators of cellular adhesion | BAUSCH + LOMB IRELAND LIMITED (IE) | 2008-07-24 | — | — | US | disclosed |
| US-7314938-B2 | Immune and/or inflammatory disorders; autoimmune disorders; disorders mediated by the CD11/CD18 family of cellular adhesion molecules (e.g., LFA-1); antagonize CD11/CD18 receptors associated with leukocytes. | SUNESIS PHARMACEUTICALS, INC. (US) | 2008-01-01 | — | — | US | disclosed |
| US-7314938-B2 | Immune and/or inflammatory disorders; autoimmune disorders; disorders mediated by the CD11/CD18 family of cellular adhesion molecules (e.g., LFA-1); antagonize CD11/CD18 receptors associated with leukocytes. | SUNESIS PHARMACEUTICALS, INC. (US) | 2008-01-01 | — | — | US | disclosed |
| WO-2006119174-A1 | METHOD FOR TREATING OCULAR DEMODEX | OCULAR SURFACE CENTER, P.A. (US) | 2006-11-09 | — | — | WO | disclosed |
| US-6326006-B1 | ACCELERATING BLOOD CIRCULATION, BODY WARMING AND RETENTION OF WARMTH; COMPRISES ALKYL PHTHALIDE, ALKOXY PHTHALIDE, ALKYLIDENE PHTHALIDE OR MIXTURE | KAO CORPORATION (JP) | 2001-12-04 | — | — | US | disclosed |
| EP-0357081-B1 | Bathing preparation | KAO CORP (JP) | 1995-01-04 | — | — | EP | disclosed |
| EP-0357081-A2 | Bathing preparation | Kao Corporation (JP) | 1990-03-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140066476-A1 | MODULATORS OF CELLULAR ADHESION | ITGB1, VCAM1, ITGB8 | ALDH1A1 112/4885KMT2A 2960/4885KDM4E 3313/4885 |
| US-20080176896-A1 | Modulators of cellular adhesion | ITGB1, VCAM1, ITGB8 | ALDH1A1 112/4885KMT2A 2960/4885KDM4E 3313/4885 |
| US-20160074381-A1 | MODULATORS OF CELLULAR ADHESION | ITGB1, VCAM1, ITGB8 | ALDH1A1 112/4885KMT2A 2960/4885KDM4E 3313/4885 |
| US-20090214676-A1 | METHOD FOR TREATING OCULAR DEMODEX | THRB, THRA, LIPE | ALDH1A1 217/4885KMT2A 4758/4885KDM4E 3790/4885 |
| US-20080182839-A1 | MODULATORS OF CELLULAR ADHESION | ITGB1, VCAM1, ITGB8 | ALDH1A1 111/4885KMT2A 2971/4885KDM4E 3330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.