Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.38 |
| ▸ | KIF11 | P52732 | 3/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | MAT2A | P31153 | 3/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23255483 | 0.96 | KIF11 (0.39) | PTGDR2KIF11IDO1PDE2APDE10A | |
| SCHEMBL23255493 | 0.92 | MAT2A (0.38) | KIF11PDE2APDE10AMAT2ATRPV1 | |
| SCHEMBL23255297 | 0.89 | KIF11 (0.36) | KIF11PDE2APDE10AMAT2ATRPV1 | |
| SCHEMBL23255446 | 0.88 | KIF11 (0.36) | KIF11IDO1PDE2APDE10ATRPV1 | |
| SCHEMBL23255448 | 0.87 | KIF11 (0.40) | KIF11PDE2APDE10AMAT2AAKT1 | |
| SCHEMBL23255447 | 0.86 | ICMT (0.36) | KIF11MAT2ATRPV1AKT1 | |
| SCHEMBL23255484 | 0.85 | KIF11 (0.40) | KIF11PDE2APDE10AMAT2ATRPV1 | |
| SCHEMBL18374375 | 0.85 | KIF11 (0.49) | PTGDR2KIF11PIK3CAPIK3CBPIK3CG | |
| SCHEMBL23255300 | 0.84 | TOP1 (0.39) | KIF11PDE2APDE10ATRPV1AKT1 | |
| SCHEMBL19795556 | 0.84 | KIF11 (0.47) | PTGDR2KIF11PIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3581570-B1 | CARBAZOLE-PYRIDINE-TRIFLUOROMETHYLPHENYL DERIVATIVES AND RELATED COMPOUNDS FOR USE AS TADF LUMINESCENT EMITTERS IN OLEDS | CYNORA GMBH (DE) | 2021-04-21 | — | — | EP | disclosed |