Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.45 |
| ▸ | RHOC | P08134 | 4/20 | 0.44 |
| ▸ | RHOA | P61586 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | NNMT | P40261 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | JUN | P05412 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23256742 | 0.87 | RHOC (0.47) | TGM2RHOCRHOAP2RX1BCHE | |
| SCHEMBL23257556 | 0.82 | TGM2 (0.50) | TGM2RHOCRHOAP2RX1BCHE | |
| SCHEMBL22446313 | 0.78 | RHOC (0.47) | TGM2RHOCRHOAP2RX1BCHE | |
| SCHEMBL22446314 | 0.76 | RHOC (0.45) | TGM2RHOCRHOAP2RX1BCHE | |
| SCHEMBL18763049 | 0.75 | TGM2 (0.69) | TGM2P2RX1TACR1GPR35LMNA | |
| SCHEMBL20857042 | 0.75 | P2RX1 (0.62) | TGM2RHOCRHOAHTTP2RX1 | |
| SCHEMBL18763027 | 0.75 | RHOC (0.44) | TGM2RHOCRHOAP2RX1BCHE | |
| SCHEMBL23257559 | 0.72 | TGM2 (0.43) | TGM2RHOCRHOAP2RX1BCHE | |
| SCHEMBL23256741 | 0.72 | MEN1 (0.57) | TGM2 | |
| SCHEMBL15541487 | 0.70 | TGM2 (0.61) | TGM2HTTP2RX1TACR1GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021076755-A1 | AN ACTIVITY-GUIDE MAP OF ELECTROPHILE-CYSTEINE INTERACTIONS IN PRIMARY HUMAN IMMUNE CELLS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-04-22 | — | — | WO | disclosed |