Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | TGM2 | P21980 | 2/20 | 0.57 |
| ▸ | RHOC | P08134 | 2/20 | 0.54 |
| ▸ | RHOA | P61586 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18763049 | 0.80 | TGM2 (0.69) | P2RX1LMNATGM2MAPTP2RX4 | |
| SCHEMBL23257556 | 0.80 | TGM2 (0.50) | P2RX1TGM2RHOCRHOATRPA1 | |
| SCHEMBL5037103 | 0.78 | ALDH1A1 (0.68) | LMNATGM2RAB9AMAPTMEN1 | |
| SCHEMBL15541487 | 0.78 | TGM2 (0.61) | P2RX1LMNATGM2MAPTHTT | |
| SCHEMBL27568768 | 0.77 | P2RX1 (0.76) | P2RX1LMNARHOCRHOARAB9A | |
| SCHEMBL23447713 | 0.77 | P2RX1 (1.00) | P2RX1LMNARAB9ANPC1KCNK3 | |
| SCHEMBL22387581 | 0.77 | LMNA (0.67) | P2RX1LMNARHOCRHOARAB9A | |
| SCHEMBL30211836 | 0.77 | TGM2 (0.96) | LMNATGM2CYP1A2 | |
| SCHEMBL16895199 | 0.76 | TGM2 (0.52) | P2RX1TGM2TRPA1CYP1A2MAPT | |
| SCHEMBL4746373 | 0.76 | ALOX5 (0.71) | LMNATGM2RAB9ANPC1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200278355-A1 | CONJUGATED PROTEINS AND USES THEREOF | SCRIPPS RESEARCH INST (US) | 2020-09-03 | — | — | US | disclosed |
| US-20200278355-A1 | CONJUGATED PROTEINS AND USES THEREOF | SCRIPPS RESEARCH INST (US) | 2020-09-03 | — | — | US | disclosed |
| EP-3688472-A1 | CONJUGATED PROTEINS AND USES THEREOF | The Scripps Research Institute (US) | 2020-08-05 | — | — | EP | disclosed |
| WO-2019067741-A1 | CONJUGATED PROTEINS AND USES THEREOF | THE SCRIPPS RESEARCH INSTITUTE (US) | 2019-04-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200278355-A1 | CONJUGATED PROTEINS AND USES THEREOF | KEAP1, GSTK1, GSTM2 | P2RX1 4676/4885LMNA 2810/4885TGM2 344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.