Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | RHOC | P08134 | 4/20 | 0.41 |
| ▸ | RHOA | P61586 | 4/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23256741 | 0.83 | MEN1 (0.57) | TGM2MEN1KMT2A | |
| SCHEMBL23256737 | 0.83 | FAAH (0.52) | TGM2NAMPTKMT2A | |
| SCHEMBL23256738 | 0.81 | CA1 (0.52) | EGFRMEN1KMT2A | |
| SCHEMBL22446313 | 0.78 | RHOC (0.47) | TGM2RHOCRHOAEGFRBCHE | |
| SCHEMBL23257556 | 0.77 | TGM2 (0.50) | TGM2RHOCRHOABCHEP2RX1 | |
| SCHEMBL22446314 | 0.75 | RHOC (0.45) | TGM2RHOCRHOAEGFRBCHE | |
| SCHEMBL18763027 | 0.74 | RHOC (0.44) | TGM2RHOCRHOANAMPTBCHE | |
| SCHEMBL23256742 | 0.73 | RHOC (0.47) | TGM2RHOCRHOAEGFRBCHE | |
| SCHEMBL23257562 | 0.73 | TRPV1 (0.61) | — | |
| SCHEMBL23257554 | 0.72 | TGM2 (0.45) | TGM2RHOCRHOAEGFRBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021076755-A1 | AN ACTIVITY-GUIDE MAP OF ELECTROPHILE-CYSTEINE INTERACTIONS IN PRIMARY HUMAN IMMUNE CELLS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-04-22 | — | — | WO | disclosed |