SCHEMBL2326286

SCHEMBL2326286

[Sn]OCCC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 15/20 0.48
KCNH2 Q12809 3/20 0.41
CYP11B1 P15538 1/20 0.38
CYP11B2 P19099 1/20 0.38
CYP2D6 P10635 2/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
CHRM4 P08173 1/20 0.35
CHRM5 P08912 1/20 0.35
CHRM3 P20309 1/20 0.35
LMNA P02545 1/20 0.35
CHRM2 P08172 1/20 0.35
HTR1A P08908 1/20 0.35
CHRM1 P11229 1/20 0.35
OPRM1 P35372 1/20 0.35
MAPK1 P28482 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2325018 0.87 KIF11 (0.55) KIF11KCNH2CYP11B1CYP11B2CYP2D6
SCHEMBL2326446 0.85 KIF11 (0.53) KIF11KCNH2CYP11B1CYP11B2CYP2D6
SCHEMBL2324748 0.84 KIF11 (0.52) KIF11KCNH2CYP11B1CYP11B2CYP2D6
SCHEMBL2328040 0.84 KIF11 (0.52) KIF11KCNH2CYP11B1CYP11B2CYP2D6
SCHEMBL2327154 0.84 KIF11 (0.52) KIF11KCNH2CYP11B1CYP11B2CYP2D6
SCHEMBL2328128 0.84 KIF11 (0.52) KIF11KCNH2CYP11B1CYP11B2CYP2D6
SCHEMBL2326451 0.84 KIF11 (0.52) KIF11KCNH2CYP11B1CYP11B2CYP2D6
SCHEMBL703111 0.77 KIF11 (0.48) KIF11KCNH2CYP11B1CYP11B2CYP2D6
SCHEMBL1149158 0.77 KIF11 (0.64) KIF11KCNH2CYP11B1CYP11B2CYP2D6
SCHEMBL2328171 0.76 KIF11 (0.41) KIF11KCNH2CYP2C9CYP2C19MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1987881-B1 METHOD FOR SEPARATION AND COLLECTION OF DIALKYL TIN DIALKOXIDE ASAHI KASEI CHEMICALS CORP (JP) 2011-08-17 EP disclosed
US-7842828-B2 Method for separating out and recovering dialkyltin dialkoxide ASAHI KASEI CHEMICALS CORPORATION (JP) 2010-11-30 US disclosed
US-20100160662-A1 Method for Separating Out and Recovering Dialkyltin Dialkoxide ASAHI KASEI KABUSHIKI KAISHA (JP) 2010-06-24 US disclosed
EP-1987881-A1 METHOD FOR SEPARATION AND COLLECTION OF DIALKYL TIN DIALKOXIDE Asahi Kasei Chemicals Corporation (JP) 2008-11-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100160662-A1 Method for Separating Out and Recovering Dialkyltin Dialkoxide ALOX5, ALOX15B, ALOX15 KIF11 4761/4885KCNH2 1319/4885CYP11B1 388/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.