Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HCK | P08631 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.32 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.32 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23269644 | 0.83 | L3MBTL1 (0.40) | ALDH1A1KDM4EKMT2APKMSLC18A3 | |
| SCHEMBL5659414 | 0.81 | ALDH1A1 (0.41) | ALDH1A1KDM4EKMT2APKMSLC18A3 | |
| SCHEMBL23269702 | 0.80 | KDM4E (0.37) | ALDH1A1KDM4EKMT2APKMSLC18A3 | |
| SCHEMBL24207800 | 0.79 | GNAI3 (0.44) | ALDH1A1KMT2ASMN1; SMN2MAPTSIGMAR1 | |
| SCHEMBL28078036 | 0.78 | GNAI3 (0.32) | ALDH1A1KDM4EKMT2APKMSMN1; SMN2 | |
| SCHEMBL24454166 | 0.78 | KMT2A (0.46) | ALDH1A1KDM4EKMT2APKMSLC18A3 | |
| SCHEMBL24351554 | 0.78 | KEAP1 (0.42) | SMN1; SMN2SIGMAR1GNAI3GNAO1GNAI1 | |
| SCHEMBL23384127 | 0.77 | LMNA (0.39) | ALDH1A1KDM4EKMT2APKMSLC18A3 | |
| SCHEMBL163306 | 0.77 | ALDH1A1 (0.52) | ALDH1A1KDM4EKMT2APKMSLC18A3 | |
| SCHEMBL7671840 | 0.77 | ALDH1A1 (0.52) | ALDH1A1KDM4EKMT2APKMSLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021076886-A1 | 3-PHENYLSULPHONYL-QUINOLINE DERIVATIVES AS AGENTS FOR TREATING PATHOGENIC BLOOD VESSELS DISORDERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-04-22 | — | — | WO | disclosed |