Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | PLAT | P00750 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2671108 | 0.94 | LMNA (0.48) | LMNAOPRK1RAB9ANPC1KDM4E | |
| SCHEMBL23289754 | 0.91 | PDE4B (0.48) | LMNAPDE4B | |
| SCHEMBL1063097 | 0.90 | LMNA (0.42) | LMNAOPRK1RAB9ANPC1KDM4E | |
| SCHEMBL23289755 | 0.88 | LMNA (0.44) | LMNAOPRK1RAB9ANPC1KDM4E | |
| SCHEMBL13887500 | 0.85 | LMNA (0.49) | LMNARAB9ANPC1KDM4EHSD17B10 | |
| SCHEMBL27869185 | 0.85 | CYP3A4 (0.43) | LMNAOPRK1RAB9ANPC1KDM4E | |
| SCHEMBL1059761 | 0.85 | LMNA (0.56) | LMNAALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL1061726 | 0.85 | GPR119 (0.45) | LMNAKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL30984273 | 0.84 | LMNA (0.48) | LMNARAB9ANPC1KDM4EHSD17B10 | |
| SCHEMBL23122360 | 0.83 | LMNA (0.47) | LMNARAB9ANPC1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114761397-B | Benzodiazepine derivatives for the treatment of Respiratory Syncytial Virus (RSV) infection | 辉瑞公司 | 2024-11-05 | — | — | CN | disclosed |
| US-20220409629-A1 | BENZODIAZEPINE DERIVATIVES FOR TREATING A RESPIRATORY SYNCYTIAL VIRUS (RSV) INFECTION | PFIZER INC. | 2022-12-29 | — | — | US | disclosed |
| US-20220409629-A1 | BENZODIAZEPINE DERIVATIVES FOR TREATING A RESPIRATORY SYNCYTIAL VIRUS (RSV) INFECTION | PFIZER INC. | 2022-12-29 | — | — | US | disclosed |
| EP-4048665-A1 | BENZODIAZEPINE DERIVATIVES FOR TREATING A RESPIRATORY SYNCYTIAL VIRUS (RSV) INFECTION | Reviral Limited (GB) | 2022-08-31 | — | — | EP | disclosed |
| CN-114761397-A | Benzodiazepine derivatives for the treatment of Respiratory Syncytial Virus (RSV) infection | 瑞威有限公司 | 2022-07-15 | — | — | CN | disclosed |
| WO-2021079121-A1 | BENZODIAZEPINE DERIVATIVES FOR TREATING A RESPIRATORY SYNCYTIAL VIRUS (RSV) INFECTION | ReViral Limited (GB) | 2021-04-29 | — | — | WO | disclosed |
| WO-2021079121-A1 | BENZODIAZEPINE DERIVATIVES FOR TREATING A RESPIRATORY SYNCYTIAL VIRUS (RSV) INFECTION | ReViral Limited (GB) | 2021-04-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220409629-A1 | BENZODIAZEPINE DERIVATIVES FOR TREATING A RESPIRATORY SYNCYTIAL VIRUS (RSV) INFECTION | GABRA1, GABRA3, CNR1 | LMNA 2278/4885OPRK1 149/4885RAB9A 523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.