Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13719744 | 0.77 | HSD11B1 (0.47) | LMNAALDH1A1SMN1; SMN2POLBMAPK1 | |
| SCHEMBL9764 | 0.76 | CTSL (0.33) | LMNAALDH1A1SMN1; SMN2POLBMAPK1 | |
| SCHEMBL15156675 | 0.74 | MAPT (0.38) | MAPTLMNAALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL15156081 | 0.73 | OPRM1 (0.43) | MAPTLMNAMAPK1HPGDRORC | |
| SCHEMBL15862653 | 0.73 | ALDH1A1 (0.40) | MAPTLMNAALDH1A1SMN1; SMN2POLB | |
| SCHEMBL3585852 | 0.70 | HSD11B1 (0.45) | MAPTLMNAALDH1A1SMN1; SMN2POLB | |
| SCHEMBL2381444 | 0.69 | CA12 (0.50) | ALDH1A1SMN1; SMN2NPSR1NPC1 | |
| SCHEMBL19966068 | 0.69 | JAK1 (0.51) | RORC | |
| SCHEMBL11198451 | 0.68 | NPSR1 (0.51) | MAPTALDH1A1SMN1; SMN2POLBMAPK1 | |
| SCHEMBL27674461 | 0.67 | ESR1 (0.46) | MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021078022-A1 | SMALL MOLECULE COMPOUND | 嘉兴特科罗生物科技有限公司 | 2021-04-29 | — | — | WO | disclosed |