Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | REN | P00797 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.42 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18256448 | 1.00 | ALDH1A1 (0.46) | ALDH1A1MAPTITGB3ITGA2BCTSS | |
| SCHEMBL18248108 | 0.92 | ALDH1A1 (0.41) | ALDH1A1MAPTITGB3ITGA2BCTSS | |
| SCHEMBL18256484 | 0.92 | ALDH1A1 (0.41) | ALDH1A1MAPTITGB3ITGA2BCTSS | |
| SCHEMBL18918265 | 0.89 | LTA4H (0.52) | ITGB3ITGA2BBCL2PPARA | |
| SCHEMBL18248052 | 0.87 | ALDH1A1 (0.48) | ALDH1A1MAPTITGB3ITGA2BCTSS | |
| SCHEMBL28518117 | 0.87 | ALDH1A1 (0.48) | ALDH1A1MAPTITGB3ITGA2BCTSS | |
| SCHEMBL8911125 | 0.87 | ALDH1A1 (0.48) | ALDH1A1MAPTITGB3ITGA2BCTSS | |
| SCHEMBL29624556 | 0.87 | ALDH1A1 (0.48) | ALDH1A1MAPTITGB3ITGA2BCTSS | |
| SCHEMBL1401223 | 0.87 | ALDH1A1 (0.48) | ALDH1A1MAPTITGB3ITGA2BCTSS | |
| SCHEMBL6600202 | 0.84 | MMP8 (0.46) | ALDH1A1CTSSRENITGA4ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3922639-A1 | ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS | Boehringer Ingelheim Animal Health USA Inc. (US) | 2021-12-15 | — | — | EP | disclosed |
| EP-3298027-B1 | ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2021-04-28 | — | — | EP | disclosed |