Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | REN | P00797 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.43 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14464224 | 0.89 | ALDH1A1 (0.39) | MMP8ALDH1A1GAARENMMP13 | |
| SCHEMBL992429 | 0.88 | REN (0.43) | ALDH1A1GAARENMMP13ITGA4 | |
| SCHEMBL8724329 | 0.88 | ITGA4 (0.49) | ALDH1A1GAARENMMP13ITGA4 | |
| SCHEMBL8724334 | 0.88 | ITGA4 (0.49) | ALDH1A1GAARENMMP13ITGA4 | |
| SCHEMBL12600955 | 0.88 | ITGA4 (0.49) | ALDH1A1GAARENMMP13ITGA4 | |
| SCHEMBL4092235 | 0.87 | ALDH1A1 (0.38) | MMP8ALDH1A1GAARENMMP13 | |
| SCHEMBL13799190 | 0.87 | ALDH1A1 (0.38) | MMP8ALDH1A1GAARENMMP13 | |
| SCHEMBL2476924 | 0.86 | MMP13 (0.46) | ALDH1A1RENMMP13ITGA4ITGB7 | |
| SCHEMBL1401042 | 0.86 | MMP13 (0.46) | ALDH1A1RENMMP13ITGA4ITGB7 | |
| SCHEMBL65502 | 0.86 | MMP13 (0.46) | ALDH1A1RENMMP13ITGA4ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1225471-C | Compounds with growth hormone releasing properties | NOVO NORDISK AS (DK) | 2005-11-02 | — | — | CN | disclosed |
| EP-0805816-B1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2004-07-28 | — | — | EP | disclosed |
| US-6350767-B1 | GROWTH HORMONE RELEASE STIMULANT | NOVO NORDISK A/S (DK) | 2002-02-26 | — | — | US | disclosed |
| US-6013658-A | ANIMAL GROWTH REGULATORS | NOVO NORDISK A/S (DK) | 2000-01-11 | — | — | US | disclosed |
| CN-1176645-A | Compounds with growth hormone releasing properties | NOVO NORDISK AS (DK) | 1998-03-18 | — | — | CN | disclosed |
| EP-0805816-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1997-11-12 | — | — | EP | disclosed |
| WO-1996022997-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1996-08-01 | — | — | WO | disclosed |