Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 1/20 | 0.44 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.30 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.30 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17442659 | 0.77 | KLKB1 (0.57) | KLKB1MAP4K1KDM4EPLA2G2A | |
| SCHEMBL27045873 | 0.69 | KDM5A (0.35) | — | |
| SCHEMBL17179179 | 0.68 | KDM4E (0.42) | KLKB1MAP4K1KDM4EPDE10APDGFRB | |
| SCHEMBL23279823 | 0.65 | KLKB1 (0.56) | KLKB1MAP4K1 | |
| SCHEMBL24469567 | 0.63 | GAK (0.44) | — | |
| SCHEMBL18458866 | 0.63 | KDM5A (0.31) | CYP1A2 | |
| SCHEMBL13728317 | 0.63 | PDGFRB (0.46) | KDM4EPDGFRBPDGFRA | |
| SCHEMBL21098120 | 0.62 | NOS3 (0.33) | — | |
| SCHEMBL19633231 | 0.62 | UHRF1 (0.43) | — | |
| SCHEMBL19992429 | 0.61 | LOX (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3169325-B1 | THERAPEUTIC INHIBITORY COMPOUNDS | ATTUNE PHARMACEUTICALS INC (US) | 2021-04-28 | — | — | EP | disclosed |