Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 2/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.34 |
| ▸ | PDXK | O00764 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 9/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | MERTK | Q12866 | 1/20 | 0.31 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9630722 | 0.75 | HSD17B1 (0.42) | NOS3NOS1NOS2 | |
| SCHEMBL21613490 | 0.74 | PSMB5 (0.46) | MAP4K4PDGFRBPDGFRAAXL | |
| SCHEMBL23319684 | 0.74 | MAP4K4 (0.44) | GRIN2BGRIN1MAP4K4 | |
| SCHEMBL24011937 | 0.73 | PDGFRB (0.43) | MAP4K4PDGFRBPDGFRA | |
| SCHEMBL24011728 | 0.72 | ESR2 (0.47) | MAP4K4 | |
| SCHEMBL11456047 | 0.71 | PDXK (0.38) | PDXKNOS3NOS1NOS2 | |
| SCHEMBL2313482 | 0.70 | TDP1 (0.42) | AXLMERTK | |
| SCHEMBL24229449 | 0.67 | PDGFRB (0.43) | MAP4K4PDGFRBPDGFRA | |
| SCHEMBL7245034 | 0.66 | NOS3 (0.46) | PDXKNOS3NOS1NOS2 | |
| SCHEMBL13366151 | 0.65 | TNKS2 (0.45) | AXLMERTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3227284-B1 | PESTICIDALLY ACTIVE AMIDE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-04-28 | — | — | EP | disclosed |