Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | APOBEC3G | Q9HC16 | 5/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1544475 | 0.81 | HSD17B10 (0.71) | HSD17B10LMNAKDM4EAPOBEC3GTDP1 | |
| SCHEMBL1544025 | 0.80 | TDP1 (0.68) | HSD17B10LMNAKDM4EAPOBEC3GTDP1 | |
| SCHEMBL1545303 | 0.79 | TDP1 (0.67) | HSD17B10LMNAKDM4EAPOBEC3GTDP1 | |
| SCHEMBL4878039 | 0.77 | HSD17B10 (0.65) | HSD17B10LMNAKDM4EAPOBEC3GTDP1 | |
| SCHEMBL919250 | 0.75 | HSD17B10 (0.73) | HSD17B10LMNAKDM4EAPOBEC3GTDP1 | |
| SCHEMBL1544445 | 0.72 | HSD17B10 (0.74) | HSD17B10LMNAKDM4EAPOBEC3GTDP1 | |
| SCHEMBL2893202 | 0.69 | HSD17B10 (0.59) | HSD17B10LMNAKDM4EAPOBEC3GTDP1 | |
| SCHEMBL2311265 | 0.69 | ALDH1A1 (0.66) | HSD17B10LMNAKDM4EAPOBEC3GTDP1 | |
| SCHEMBL5050462 | 0.68 | ALDH1A1 (0.54) | HSD17B10LMNAKDM4EAPOBEC3GTDP1 | |
| SCHEMBL31119462 | 0.68 | ALDH1A1 (0.60) | HSD17B10LMNAKDM4EAPOBEC3GTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2070922-B1 | Azabicyclo(3.1.0) hexane derivatives useful as modulators of dopamine D3 receptors | GLAXO GROUP LTD (GB) | 2011-08-17 | — | — | EP | claimed |
| EP-2070922-A1 | Azabicyclo(3.1.0) hexane derivatives useful as modulators of dopamine D3 receptors | GLAXO GROUP LIMITED (GB) | 2009-06-17 | — | — | EP | claimed |
| US-20210053957-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-02-25 | — | — | US | disclosed |
| US-20210053957-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-02-25 | — | — | US | disclosed |
| EP-3774779-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-02-17 | — | — | EP | disclosed |
| CN-111836806-A | Herbicidal compounds | 先正达参股股份有限公司 | 2020-10-27 | — | — | CN | disclosed |
| WO-2019185875-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-10-03 | — | — | WO | disclosed |
| WO-2019185875-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-10-03 | — | — | WO | disclosed |
| EP-2007747-B1 | PROCESS FOR PREPARING HETEROCYCLIC DERIVATIVES | GLAXO GROUP LTD (GB) | 2013-11-20 | — | — | EP | disclosed |
| US-7838680-B2 | Process for preparing heterocyclic derivatives | GLAXO GROUP LIMITED (GB) | 2010-11-23 | — | — | US | disclosed |
| US-20100048895-A1 | Process for Preparing Heterocyclic Derivatives | GLAXO GROUP LIMITED (GB) | 2010-02-25 | — | — | US | disclosed |
| US-20070232808-A1 | PROCESS FOR PREPARING HETEROCYCLIC DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2007-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210053957-A1 | HERBICIDAL COMPOUNDS | DDT, ACHE, GSTO1 | HSD17B10 184/4885LMNA 3858/4885KDM4E 1233/4885 |
| US-20100048895-A1 | Process for Preparing Heterocyclic Derivatives | HCAR3, CBR3, HRH4 | HSD17B10 1010/4885LMNA 3599/4885KDM4E 4425/4885 |
| US-20070232808-A1 | PROCESS FOR PREPARING HETEROCYCLIC DERIVATIVES | HCAR3, CBR3, NR4A3 | HSD17B10 949/4885LMNA 3444/4885KDM4E 4646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.