SCHEMBL2328276

SCHEMBL2328276

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)[n+]1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2325593 0.97 LMNA (0.38) LMNA
SCHEMBL2330785 0.97 LMNA (0.38) LMNA
SCHEMBL2319735 0.97 LMNA (0.38) LMNA
SCHEMBL2323753 0.97 LMNA (0.38) LMNA
SCHEMBL2330239 0.92
SCHEMBL2329383 0.80
Bromide SCHEMBL18094951 0.72 LMNA (0.33) LMNA
SCHEMBL11322368 0.67
SCHEMBL2318874 0.66 LMNA (0.32) LMNA
Bromide SCHEMBL29205001 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7989535-B2 Surface-modified nanofiller and polymer composite material DAIKIN INDUSTRIES, LTD. (JP) 2011-08-02 US disclosed
US-20100160503-A1 SURFACE-MODIFIED NANOFILLER AND POLYMER COMPOSITE MATERIAL DAIKIN INDUSTRIES, LTD, (JP) 2010-06-24 US disclosed
US-7649118-B2 Process for preparing fluorine-containing norbornene derivative DAIKIN INDUSTRIES, LTD. (JP) 2010-01-19 US disclosed
EP-1908801-A1 SURFACE-MODIFIED NANOFILLER AND POLYMER COMPOSITE MATERIAL Daikin Industries, Ltd. (JP) 2008-04-09 EP disclosed
US-20070129576-A1 Process for preparing fluorine-containing norbornene derivative DAIKIN INDUSTRIES, LTD. 2007-06-07 US disclosed
US-7186773-B2 Process for preparing fluorine-containing norbornene derivative DAIKIN INDUSTRIES, LTD. (JP) 2007-03-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070129576-A1 Process for preparing fluorine-containing norbornene derivative ADH1A, FLNA, FFAR2 LMNA 904/4885
US-20100160503-A1 SURFACE-MODIFIED NANOFILLER AND POLYMER COMPOSITE MATERIAL FSCN1, FLNB, FLNA LMNA 1936/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.