SCHEMBL2328583

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6211997	0.96	CA1 (0.52)	TDP1CA1CA2SIGMAR1RARB
	SCHEMBL379892	0.90	CA2 (0.54)	TDP1CA1CA2SIGMAR1MEN1
	SCHEMBL2333929	0.88	CYP4A11 (0.58)	TDP1CA1CA2SIGMAR1GAA
	SCHEMBL4961185	0.87	SIGMAR1 (0.62)	TDP1SIGMAR1MEN1KMT2AGAA
	SCHEMBL31307112	0.86	TDP1 (0.54)	TDP1CA1CA2SIGMAR1MEN1
	SCHEMBL22102023	0.86	NPSR1 (0.61)	TDP1SIGMAR1MEN1KMT2AGAA
	SCHEMBL31307113	0.86	TDP1 (0.58)	TDP1CA1CA2SIGMAR1MEN1
	SCHEMBL29301875	0.86	TDP1 (0.54)	TDP1CA1CA2MEN1KMT2A
	SCHEMBL5468072	0.86	NPSR1 (0.61)	TDP1SIGMAR1MEN1KMT2AGAA
	SCHEMBL917871	0.86	TDP1 (0.54)	TDP1CA1CA2SIGMAR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.