Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23287003 | 0.87 | PTGER4 (0.53) | PTGER4ALDH1A1MAPTRAB9AHCAR3 | |
| SCHEMBL23490760 | 0.85 | PTGER4 (0.51) | PTGER4ALDH1A1MAPTRAB9AHCAR3 | |
| SCHEMBL23273555 | 0.81 | PTGER4 (0.57) | PTGER4ALDH1A1MAPTRAB9AHCAR3 | |
| SCHEMBL29738069 | 0.77 | MAPT (0.60) | PTGER4ALDH1A1MAPTRAB9AHCAR3 | |
| SCHEMBL23286252 | 0.77 | MAPT (0.60) | PTGER4ALDH1A1MAPTRAB9AHCAR3 | |
| SCHEMBL23286926 | 0.73 | PTGER4 (0.56) | PTGER4ALDH1A1MAPTRAB9AHCAR3 | |
| SCHEMBL21015886 | 0.73 | HPGD (0.59) | ALDH1A1MAPTRAB9AHPGDMEN1 | |
| SCHEMBL23287088 | 0.72 | SLC7A5 (0.40) | PTGER4ALDH1A1MAPTALOX15HPGD | |
| SCHEMBL24956357 | 0.71 | ALOX15 (0.43) | PTGER4ALDH1A1MAPTRAB9AALOX15 | |
| SCHEMBL29160321 | 0.71 | ALOX15 (0.43) | PTGER4ALDH1A1MAPTRAB9AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021081207-A1 | GLP-1R MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2021-04-29 | — | — | WO | disclosed |