Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29459383 | 1.00 | SMN1; SMN2 (0.41) | SMN1; SMN2PDGFRBPDGFRAITGB3ITGA2B | |
| SCHEMBL2328850 | 0.77 | KMT2A (0.44) | SMN1; SMN2PDGFRBPDGFRAKMT2AMEN1 | |
| SCHEMBL24325919 | 0.74 | SMN1; SMN2 (0.69) | SMN1; SMN2ATML3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL14075128 | 0.71 | RAB9A (0.55) | SMN1; SMN2PDGFRBPDGFRAKMT2AMEN1 | |
| SCHEMBL2327636 | 0.70 | KMT2A (0.44) | SMN1; SMN2PDGFRBPDGFRAKMT2AMEN1 | |
| SCHEMBL2327633 | 0.70 | KMT2A (0.44) | SMN1; SMN2PDGFRBPDGFRAKMT2AMEN1 | |
| SCHEMBL531060 | 0.69 | TRPV1 (0.41) | SMN1; SMN2KMT2AMEN1HDAC3HDAC4 | |
| SCHEMBL23491381 | 0.69 | RAB9A (0.41) | SMN1; SMN2PDGFRBPDGFRAKMT2AMEN1 | |
| SCHEMBL5462379 | 0.69 | CYP1A2 (0.44) | SMN1; SMN2PDGFRBPDGFRAKMT2ACYP1A2 | |
| SCHEMBL372069 | 0.69 | CYP1A2 (0.44) | SMN1; SMN2PDGFRBPDGFRAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113614074-A | Amino acid derivatives for the treatment of inflammatory diseases | 罗斯坎普研究所 | 2021-11-05 | — | — | CN | disclosed |