Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23288565 | 0.85 | ALOX5 (0.45) | ALDH1A1KMT2AALOX5MMP3MMP2 | |
| SCHEMBL23288566 | 0.80 | FFAR1 (0.41) | ALDH1A1KMT2AALOX5FFAR1MMP3 | |
| SCHEMBL23288561 | 0.78 | FFAR1 (0.43) | ALDH1A1KMT2AALOX5FFAR1MMP3 | |
| SCHEMBL503646 | 0.71 | ALOX5 (0.68) | ALDH1A1KMT2AALOX5FFAR1FFAR4 | |
| SCHEMBL10165844 | 0.70 | ALOX5 (0.62) | ALDH1A1KMT2AALOX5 | |
| SCHEMBL9330077 | 0.69 | CNR1 (0.51) | ALDH1A1ALOX5MMP3MMP2S1PR1 | |
| SCHEMBL10416276 | 0.69 | ALOX5 (0.60) | ALDH1A1KMT2AALOX5 | |
| SCHEMBL15279138 | 0.68 | CALM1 (0.51) | ALDH1A1KMT2AALOX5LMNAL3MBTL1 | |
| SCHEMBL12459723 | 0.68 | L3MBTL1 (0.64) | ALDH1A1KMT2AALOX5LMNAL3MBTL1 | |
| SCHEMBL28543983 | 0.67 | MAPT (0.58) | ALDH1A1FFAR1FFAR4S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021081315-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF CRYPTOSPORIDIOSIS | THE BROAD INSTITUTE, INC. (US) | 2021-04-29 | — | — | WO | disclosed |