Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.40 |
| ▸ | BMP1 | P13497 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23288508 | 0.85 | ALDH1A1 (0.41) | ALOX5ALDH1A1KMT2AMMP3MMP2 | |
| SCHEMBL23288554 | 0.75 | FFAR1 (0.44) | ALDH1A1KMT2AMMP3MMP2 | |
| SCHEMBL10165844 | 0.74 | ALOX5 (0.62) | ALOX5ALDH1A1KMT2AF2RL1 | |
| SCHEMBL23288567 | 0.74 | FFAR1 (0.43) | ALOX5ALDH1A1KMT2AMMP3 | |
| SCHEMBL9330077 | 0.73 | CNR1 (0.51) | ALOX5ALDH1A1MMP3MMP2F2RL1 | |
| SCHEMBL10416276 | 0.73 | ALOX5 (0.60) | ALOX5ALDH1A1KMT2AF2RL1 | |
| SCHEMBL15279138 | 0.73 | CALM1 (0.51) | ALOX5ALDH1A1KMT2A | |
| SCHEMBL12427784 | 0.71 | SLC6A4 (0.55) | KMT2A | |
| SCHEMBL28775909 | 0.70 | ALOX5 (0.60) | ALOX5ALDH1A1KMT2AF2RL1 | |
| SCHEMBL6989069 | 0.70 | CALM1 (0.56) | ALOX5ALDH1A1KMT2AF2RL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021081315-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF CRYPTOSPORIDIOSIS | THE BROAD INSTITUTE, INC. (US) | 2021-04-29 | — | — | WO | disclosed |