Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.44 |
| ▸ | PTGES | O14684 | 4/20 | 0.44 |
| ▸ | ACACB | O00763 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 3/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.35 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.35 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.35 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23288567 | 0.90 | FFAR1 (0.43) | FFAR1PTGESACACBALDH1A1KMT2A | |
| SCHEMBL23288537 | 0.82 | FFAR1 (0.46) | FFAR1PTGESACACBALDH1A1KMT2A | |
| SCHEMBL23288565 | 0.75 | ALOX5 (0.45) | ALDH1A1KMT2AMMP3MMP2 | |
| SCHEMBL23288559 | 0.72 | FFAR1 (0.41) | FFAR1PTGESALDH1A1KMT2AMMP3 | |
| SCHEMBL23288508 | 0.72 | ALDH1A1 (0.41) | FFAR1ALDH1A1KMT2AMMP3MMP2 | |
| SCHEMBL23288566 | 0.71 | FFAR1 (0.41) | FFAR1PTGESACACBALDH1A1KMT2A | |
| SCHEMBL23288561 | 0.70 | FFAR1 (0.43) | FFAR1PTGESALDH1A1KMT2AMMP3 | |
| SCHEMBL23288517 | 0.69 | FFAR1 (0.43) | FFAR1PTGESACACBALDH1A1KMT2A | |
| SCHEMBL23288524 | 0.68 | FFAR1 (0.41) | FFAR1PTGESACACBALDH1A1KMT2A | |
| SCHEMBL27836396 | 0.68 | FFAR1 (0.85) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021081315-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF CRYPTOSPORIDIOSIS | THE BROAD INSTITUTE, INC. (US) | 2021-04-29 | — | — | WO | disclosed |