SCHEMBL232895

SCHEMBL232895

CCCCOc1ccc(S(=O)(=O)Cl)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.68
CA12 O43570 4/20 0.68
CA1 P00915 4/20 0.68
CA2 P00918 4/20 0.68
CA9 Q16790 4/20 0.68
CA7 P43166 3/20 0.68
MAPK1 P28482 2/20 0.55
RECQL P46063 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
NPC1 O15118 2/20 0.51
RAB9A P51151 2/20 0.51
SMN1; SMN2 Q16637 6/20 0.51
HTT P42858 5/20 0.51
MMP1 P03956 2/20 0.51
CYP3A4 P08684 2/20 0.51
CYP2D6 P10635 2/20 0.51
ADAMTS4 O75173 1/20 0.51
MMP2 P08253 1/20 0.51
MMP13 P45452 1/20 0.51
MMP14 P50281 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL991363 0.96 TSHR (0.64) TSHRCA12CA1CA2CA9
SCHEMBL7766693 0.95 TSHR (0.62) TSHRCA12CA1CA2CA9
SCHEMBL10608025 0.95 TSHR (0.62) TSHRCA12CA1CA2CA9
SCHEMBL10600260 0.95 TSHR (0.62) TSHRCA12CA1CA2CA9
SCHEMBL10708683 0.95 TSHR (0.62) TSHRCA12CA1CA2CA9
SCHEMBL10606406 0.95 TSHR (0.62) TSHRCA12CA1CA2CA9
SCHEMBL10606881 0.95 TSHR (0.62) TSHRCA12CA1CA2CA9
SCHEMBL3369946 0.95 TSHR (0.62) TSHRCA12CA1CA2CA9
SCHEMBL10610971 0.95 TSHR (0.62) TSHRCA12CA1CA2CA9
SCHEMBL1111500 0.95 TSHR (0.62) TSHRCA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 369 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4692062-A1 NOVEL AMIDE-BASED COMPOUND AND COMPOSITION COMPRISING SAME Amorepacific Corporation (KR) 2026-02-11 EP claimed
WO-2024205303-A1 NOVEL AMIDE-BASED COMPOUND AND COMPOSITION COMPRISING SAME (주)아모레퍼시픽 2024-10-03 WO claimed
CN-111100044-B Preparation method of alkyl zinc sulfinate series compounds 鹤壁元昊化工有限公司 2020-10-16 CN claimed
EP-1377589-B1 OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS PHARMACIA ITALIA SPA (IT) 2005-09-07 EP claimed
US-20260144730-A1 COMPOSITION FOR SKIN ANTI-AGING, SKIN BRIGHTENING OR SKIN REVERSE-AGING CONTAINING AMIDE-BASED COMPOUND AMOREPACIFIC CORPORATION (KR) 2026-05-28 US disclosed
US-20260083715-A1 COMPOSITION FOR ENHANCING IMMUNITY CONTAINING AMIDE-BASED COMPOUND AMOREPACIFIC CORPORATION (KR) 2026-03-26 US disclosed
US-12583818-B2 Compound, preparation method thereof, and use thereof DAEGU-GYEONGBUK MEDICAL INNOVATION FOUNDATION (KR) 2026-03-24 US disclosed
EP-4692062-A1 NOVEL AMIDE-BASED COMPOUND AND COMPOSITION COMPRISING SAME Amorepacific Corporation (KR) 2026-02-11 EP disclosed
CN-119462588-A Flavone derivative containing sulfonamide structure and preparation method and application thereof 上海中医药大学附属曙光医院 2025-02-18 CN disclosed
CN-119219808-A Multifunctional ionic polymer, preparation method and application thereof, and ion exchange membrane 佛山绿动氢能科技有限公司 2024-12-31 CN disclosed
CN-114981241-B Novel compounds, process for their preparation and their use 大邱庆北尖端医疗产业振兴财团 2024-11-19 CN disclosed
WO-2024205303-A1 NOVEL AMIDE-BASED COMPOUND AND COMPOSITION COMPRISING SAME (주)아모레퍼시픽 2024-10-03 WO disclosed
US-4874894-A Process for the production of benzenesulfonamides HILTON DAVIS CO. (US) 1989-10-17 US disclosed
US-4792542-A CONTAINING AN AROMATIC SULFIDE FUJI PHOTO FILM CO., LTD. (JP) 1988-12-20 US disclosed
EP-0222343-A2 Recording material FUJI PHOTO FILM CO., LTD. (JP) 1987-05-20 EP disclosed
US-4522739-A FOR USE IN LOW TEMPERATURES, AROMATIC SULFONYL FLURIDE COLGATE-PALMOLIVE COMPANY (US) 1985-06-11 US disclosed
US-4292191-A Activated peroxy compound bleaching compositions and bleaching detergent compositions COLGATE-PALMOLIVE COMPANY (US) 1981-09-29 US disclosed
US-4107065-A P-ACYLAMINOBENZENESULFONYL CHLORIDE OR BROMIDE COLGATE-PALMOLIVE COMPANY (US) 1978-08-15 US disclosed
US-4041051-A 1-AMINO-4-HYDROXY-2-(P-METHOXY OR ETHOXY-BENZENESULFONYLOXY)-ANTHRAQUINONE SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-08-09 US disclosed
US-3935218-A Imidazolinyl phenyl carbonyl compounds acid addition salts and related compounds AMERICAN HOME PRODUCTS CORPORATION (US) 1976-01-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260144730-A1 COMPOSITION FOR SKIN ANTI-AGING, SKIN BRIGHTENING OR SKIN REVERSE-AGING CONTAINING AMIDE-BASED COMPOUND TYR, ATG13, ARGLU1 TSHR 3528/4885CA12 4446/4885CA1 2417/4885
US-12583818-B2 Compound, preparation method thereof, and use thereof TYRO3, TH, SRMS TSHR 565/4885CA12 2090/4885CA1 1920/4885
US-20260083715-A1 COMPOSITION FOR ENHANCING IMMUNITY CONTAINING AMIDE-BASED COMPOUND ARG1, MSR1, TLR1 TSHR 2921/4885CA12 3357/4885CA1 741/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.