Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 2/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23291866 | 0.87 | NT5E (0.38) | NT5EHDAC6RORCSMN1; SMN2TTR | |
| SCHEMBL30112575 | 0.83 | NT5E (0.41) | NT5EHDAC6RORCSMN1; SMN2TTR | |
| SCHEMBL24942496 | 0.83 | NT5E (0.41) | NT5EHDAC6RORCSMN1; SMN2TTR | |
| SCHEMBL31696933 | 0.81 | NT5E (0.37) | NT5EMAPK14HDAC6RORCTTR | |
| SCHEMBL13435046 | 0.80 | KMT2A (0.53) | NT5ERORCSMN1; SMN2TTRHPGD | |
| SCHEMBL18526322 | 0.80 | NT5E (0.41) | NT5EHDAC6RORCSMN1; SMN2TTR | |
| SCHEMBL22126287 | 0.80 | KMT2A (0.36) | NT5EMAPK14SMN1; SMN2RAB9AHTT | |
| SCHEMBL18526325 | 0.79 | NT5E (0.40) | NT5EHDAC6RORCTTRJAK2 | |
| SCHEMBL34465270 | 0.78 | PRMT1 (0.49) | NT5EHDAC6RORCSMN1; SMN2TTR | |
| SCHEMBL995937 | 0.78 | FTO (0.49) | NT5ERORCTTRJAK2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3816180-A1 | CIRCULARLY PERMUTATED HALOALKANE TRANSFERASE FUSION MOLECULES | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2021-05-05 | — | — | EP | disclosed |