SCHEMBL2329268

SCHEMBL2329268

CC(F)C(F)(F)C(F)(F)[Sn](=O)OCc1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.34
MAOB P27338 1/20 0.34
TSHR P16473 3/20 0.33
KMT2A Q03164 2/20 0.33
MAPK1 P28482 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A3 Q01959 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
MEN1 O00255 1/20 0.33
CTSL P07711 1/20 0.32
CTSS P25774 1/20 0.32
IDO1 P14902 1/20 0.32
LMNA P02545 2/20 0.31
HPGD P15428 1/20 0.31
HTT P42858 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2325434 0.76 TSHR (0.36) ALDH1A1TSHRKMT2AMAPK1L3MBTL1
SCHEMBL2326003 0.75
SCHEMBL2325425 0.74 TSHR (0.34) ALDH1A1TSHRKMT2AMAPK1L3MBTL1
SCHEMBL2325429 0.71 TSHR (0.34) ALDH1A1TSHRKMT2AMAPK1L3MBTL1
SCHEMBL2329276 0.70 TSHR (0.36) ALDH1A1TSHRKMT2AMAPK1L3MBTL1
SCHEMBL2327784 0.69 TSHR (0.35) ALDH1A1TSHRMAPK1L3MBTL1SLC6A2
SCHEMBL2328694 0.69 TSHR (0.35) ALDH1A1TSHRMAPK1IDO1LMNA
SCHEMBL2328881 0.68 TACR1 (0.34) KMT2ASLC6A2SLC6A3TDP1MEN1
SCHEMBL2345113 0.67 TSHR (0.33) ALDH1A1TSHRMAPK1IDO1LMNA
SCHEMBL20934789 0.65 ALDH1A1 (0.55) ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1987881-B1 METHOD FOR SEPARATION AND COLLECTION OF DIALKYL TIN DIALKOXIDE ASAHI KASEI CHEMICALS CORP (JP) 2011-08-17 EP disclosed
US-7842828-B2 Method for separating out and recovering dialkyltin dialkoxide ASAHI KASEI CHEMICALS CORPORATION (JP) 2010-11-30 US disclosed
US-20100160662-A1 Method for Separating Out and Recovering Dialkyltin Dialkoxide ASAHI KASEI KABUSHIKI KAISHA (JP) 2010-06-24 US disclosed
EP-1987881-A1 METHOD FOR SEPARATION AND COLLECTION OF DIALKYL TIN DIALKOXIDE Asahi Kasei Chemicals Corporation (JP) 2008-11-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100160662-A1 Method for Separating Out and Recovering Dialkyltin Dialkoxide ALOX5, ALOX15B, ALOX15 ALDH1A1 970/4885MAOB 601/4885TSHR 3272/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.